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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
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866-206-6909 (Toll Free North America)
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PathPlusTM ACVR2 / ACVR2A Antibodies
ACVR2A (activing A type 2 receptor) is a transmembrane receptor that binds activin and acts as a growth and differentiation factor during development. ACVR2A also drives oligodendrocyte differentiation and myelination, and the ACVR2A/ACVR2B signaling pathway functions to regulate myelin repair after brain injury in infants. Dysregulation of ACVR2A expression is relevant to neurological disorders such as cerebral palsy and multiple sclerosis. ACVR2A is associated with susceptibility to preeclampsia and also with addiction; it is upregulated during withdrawal from and after re-exposure to some addictive drug stimulants. In immunohistochemistry, ACVR2A has cytoplasmic and membranous positivity in all tissues. References: Science Signaling. 2015. 8(386), ec196, DOI: 10.1126/scisignal.aad0323; Front Neurosci. 2018; 12: 697, PMID: 30356877; Acta Neuropathol. 2018; 135(6): 887–906, PMID: 29397421; Proc. Natl. Acad. Sci. U.S.A. 102 (50): 18117–22, PMID: 16330774;

3 PathPlusTM Antibodies
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ACVR2 / ACVR2A Antibody - Anti-ACVR2A antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
Rabbit Polyclonal to Human ACVR2 / ACVR2A
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200µl   $425.00
ACVR2 / ACVR2A Antibody - Anti-ALK-1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Select
Neuroscience
Rabbit Polyclonal to Human ACVR2 / ACVR2A
Human
IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
ACVR2 / ACVR2A Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
Rabbit Polyclonal to Human ACVR2 / ACVR2A
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00

Viewing 1-3 of 3 items