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PathPlusTM ACTA1 / Skeletal Muscle Actin Antibodies
Muscle actin (ACTA1, ACTA) is a protein that is a major component of the contractile apparatus of the cytoskeleton in muscle tissues. Mutations of the ACTA1 gene result in nemaline myopathy type 3. It is expressed in skeletal muscle, smooth muscle, heart muscle, myoepithelial cells, myofibroblasts, pericytes, and decidual cells. Staining is used to identify skeletal muscle and smooth muscle cells in normal tissues and in disease to distinguish soft-tissue tumors with muscle differentiation (eg, rhabdomyoma, rhabdomyosarcoma, leiomyoma, leiomyosarcoma) from other types of tumors. References: Am J Clin Pathol. 1991;96(1):32-45. PMID: 1712542; Cardiovasc Pathol. 2006;15(2):91-99. doi: 10.1016/j.carpath.2005.11.006; Am J Otolaryngol. 2005;26(3):201-206. PMID: 15858778; Nat Genet. 1999;23(2):208-212. doi: 10.1038/13837

1 PathPlusTM Antibody
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ACTA1 / Skeletal Muscle Actin Antibody - Anti-ACTA1 / ASMA antibody IHC of human lung, bronchial smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal Antibody
Fish, Zebrafish, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$440
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