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| Catalog Number | Size | Price |
|---|---|---|
| LS-B11171-100 | 100 µg (0.5 mg/ml) | $485 |
1 of 2
2 of 2
PathPlus™ Polyclonal Goat anti‑Human TNFRSF14 / CD270 / HVEM Antibody (200‑280 aa, Internal, IHC, WB) LS‑B11171
PathPlus™ Polyclonal Goat anti‑Human TNFRSF14 / CD270 / HVEM Antibody (200‑280 aa, Internal, IHC, WB) LS‑B11171
Note: This antibody replaces LS-C54987
Antibody:
TNFRSF14 / CD270 / HVEM Goat anti-Human Polyclonal (200-280 aa, Internal) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
TNFRSF14 / CD270 / HVEM Goat anti-Human Polyclonal (200-280 aa, Internal) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
CD270 (also called tumor necrosis factor receptor superfamily member 14, TNFRSF14, herpes virus entry mediator A, HVEM) is a cell-surface receptor and member of the TNF-receptor superfamily. It binds four distinct ligands as well as herpes simplex virus and is involved in complex signaling pathways. CD270 is involved in the pathogenesis of various autoimmune, inflammatory, and neoplastic diseases. It is broadly expressed in many tissues as well as B cells, monocytes, and T cells. Mutations are associated with pediatric follicular lymphomas and with poor prognosis in follicular lymphomas.
References: Nat Immunol. 2008;9(2):176-185. doi: 10.1038/ni1554; J Immunol. 2009;183(11):7286-7296. doi: 10.4049/jimmunol.0902490; Nat Rev Immunol. 2006;6(9):671-681. doi: 10.1038/nri1917; Front Immunol. 2019;10:617. doi:10.3389/fimmu.2019.00617; Haematologica 2013 98(8):1237;Cancer Res 2010 70(22):9166
Target
Human TNFRSF14 / CD270 / HVEM
Synonyms
TNFRSF14 | CD270 | CD270 antigen | CD40-like protein | Herpesvirus entry mediator | Herpesvirus entry mediator A | HVEM | LIGHTR | Herpes virus entry mediator A | TR2 | ATAR | HVEA
Host
Goat
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
Peptide within the internal region of TNFRSF14 / CD270.
Epitope
200-280 aa, Internal
Specificity
Human TNFRSF14.
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot (0.03 - 0.1 µg/ml)
- Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TNFRSF14 / CD270 / HVEM
Validation
Anti-TNFRSF14 / CD270 / HVEM antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-TNFRSF14 / CD270 / HVEM antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
PathPlus™ TNFRSF14 / CD270 / HVEM Antibody (200-280 aa, Internal) for IHC, WB/Western LS-B11171 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/23/2024
Date Requested: 4/23/2024
