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Catalog Number Size Price
LS-A10972-50 50 µg (1 mg/ml) $460 
TJP1 / ZO-1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PathPlus™ Polyclonal Rabbit anti‑Human TJP1 / ZO‑1 Antibody (IHC) LS‑A10972

PathPlus™ Polyclonal Rabbit anti‑Human TJP1 / ZO‑1 Antibody (IHC) LS‑A10972

Antibody:
TJP1 / ZO-1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-A10972-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
TJP1 / ZO-1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P
Format:
Unconjugated, Unmodified

Specifications

Description
TJP1 (Tight junction protein-1, Zonula occludens-1, ZO-1) is a scaffold protein involved in tight junction assembly, anchoring and stabilization. It functions in cell-cell junction signal transduction and in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells. TJP1 is upregulated in and drug-resistant multiple myeloma, and is associated with a higher risk subset of cancers. TJP1 has been found to be upregulated in drug-resistant tumors. In immunohistochemistry of normal tissue, TJP1 has membranous positivity in endothelial cells, glandular epithelia, renal glomeruli, sertoli cells, and is expressed in most tissues throughout the body. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; Oncoscience. 2017 Jul; 4(7-8): 79–94, PMID: 28966941
Target
Human TJP1 / ZO-1
Synonyms
TJP1 | ZO-1 | Zona occludens protein 1 | Zona occludens 1 | Zonula occludens protein 1 | Tight junction protein 1 | ZO1 | Tight junction protein ZO-1 | Zonula occludens 1 protein
Host
Rabbit
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
LP-10972, synthetic peptide
Applications
  • IHC - Paraffin (2.5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TJP1 / ZO-1
Q07157 NM_003257 NP_003248.3

Validation

TJP1 / ZO-1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

TJP1 / ZO-1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

TJP1 / ZO-1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

TJP1 / ZO-1 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ TJP1 / ZO-1 Antibody for IHC LS-A10972 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/15/2024