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Catalog Number Size Price
LS-B9774-300 300 µg (3 mg/ml) $440 
TJP1 / ZO-1 Antibody - HumanTestis: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Immunofluorescence of primary RPE cells with ZO1 Ab at 1:100 dilution;
TJP1 / ZO-1 Antibody - Anti-ZO1 Ab at 1:2,500 dilution; 50 ug of total protein per lane; rabbit polyclonal to goat IgG (HRP) at 1:10,000 dilution;
TJP1 / ZO-1 Antibody - HumanTestis: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
TJP1 / ZO-1 Antibody - Immunofluorescence of primary RPE cells with ZO1 Ab at 1:100 dilution;
TJP1 / ZO-1 Antibody - Anti-ZO1 Ab at 1:2,500 dilution; 50 ug of total protein per lane; rabbit polyclonal to goat IgG (HRP) at 1:10,000 dilution;
1 of 4
2 of 4
3 of 4
4 of 4

PathPlus™ Polyclonal Goat anti‑Human TJP1 / ZO‑1 Antibody (C‑Terminus, IHC, IF, WB) LS‑B9774

PathPlus™ Polyclonal Goat anti‑Human TJP1 / ZO‑1 Antibody (C‑Terminus, IHC, IF, WB) LS‑B9774

Note: This antibody replaces LS-C204268
Antibody:
TJP1 / ZO-1 Goat anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, IHC-Fr, IF, WB
Reactivity:
Human, Monkey, Mouse, Rat, Dog
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B9774-300
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
TJP1 / ZO-1 Goat anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, IHC-Fr, IF, WB
Reactivity:
Human, Monkey, Mouse, Rat, Dog
Format:
Unconjugated, Unmodified

Specifications

Description
TJP1 (Tight junction protein-1, Zonula occludens-1, ZO-1) is a scaffold protein involved in tight junction assembly, anchoring and stabilization. It functions in cell-cell junction signal transduction and in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells. TJP1 is upregulated in and drug-resistant multiple myeloma, and is associated with a higher risk subset of cancers. TJP1 has been found to be upregulated in drug-resistant tumors. In immunohistochemistry of normal tissue, TJP1 has membranous positivity in endothelial cells, glandular epithelia, renal glomeruli, sertoli cells, and is expressed in most tissues throughout the body. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; Oncoscience. 2017 Jul; 4(7-8): 79–94, PMID: 28966941
Target
Human TJP1 / ZO-1
Synonyms
TJP1 | ZO-1 | Zona occludens protein 1 | Zona occludens 1 | Zonula occludens protein 1 | Tight junction protein 1 | ZO1 | Tight junction protein ZO-1 | Zonula occludens 1 protein
Host
Goat
Reactivity
Human, Monkey, Mouse, Rat, Dog (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Purified recombinant peptide derived from within residues 1580 aa to the C-Terminus of human ZO-1 produced in E. coli.
Epitope
C-Terminus
Specificity
Detects endogenous levels of total ZO-1 by Western blot in whole cell and tissue lysates.
Applications
  • IHC
  • IHC - Paraffin (5 - 10 µg/ml)
  • IHC - Frozen (1:50 - 1:200)
  • Immunofluorescence (1:50 - 1:250)
  • Western blot (1:500 - 1:2000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.05% Sodium Azide, 20% Glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TJP1 / ZO-1
Q07157 NM_003257 NP_003248.3

Validation

TJP1 / ZO-1 Antibody - HumanTestis: Formalin-Fixed, Paraffin-Embedded (FFPE)
HumanTestis: Formalin-Fixed, Paraffin-Embedded (FFPE)
HumanTestis: Formalin-Fixed, Paraffin-Embedded (FFPE)

TJP1 / ZO-1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ TJP1 / ZO-1 Antibody (C-Terminus) for IHC, IF/Immunofluorescence, WB/Western LS-B9774 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/12/2021