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Catalog Number Size Price
LS-A1030-50 50 µg (1 mg/ml) $460 
SIPR3 / EDG3 / S1P3 Antibody - Prostate, Carcinoma
SIPR3 / EDG3 / S1P3 Antibody - Ovary, carcinoma
SIPR3 / EDG3 / S1P3 Antibody - Anti-EDG3 / S1P3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
SIPR3 / EDG3 / S1P3 Antibody - Prostate, Carcinoma
SIPR3 / EDG3 / S1P3 Antibody - Ovary, carcinoma
SIPR3 / EDG3 / S1P3 Antibody - Anti-EDG3 / S1P3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human SIPR3 / EDG3 / S1P3 Antibody (N‑Terminus, IHC) LS‑A1030

PathPlus™ Polyclonal Rabbit anti‑Human SIPR3 / EDG3 / S1P3 Antibody (N‑Terminus, IHC) LS‑A1030

Antibody:
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-A1030-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
S1PR3 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It is thought to participate in regulating vascular endothelial cell function and angiogenesis. When expressed in rat HTC4 hepatoma cells, it is capable of mediating S1P-induced cell proliferation and the suppression of apoptosis. Metastatic cancers in the brain can overexpress S1PR3 as part of the neuroinflammatory response, and it is implicated in regulating blood brain barrier permeability. In immunohistochemistry, it has variable membranous positivity in most tissues throughout the body. References: Nat Commun 9, 2705 (2018) doi:10.1038/s41467-018-05030-w
Target
Human SIPR3 / EDG3 / S1P3
Synonyms
S1PR3 | EDG-3 | EDG3 | LPB3 | S1P receptor EDG3 | S1P3 | S1P receptor Edg-3 | S1P receptor 3
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from N-Terminus extracellular domain of human EDG3 / S1P3. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey (93%); Gorilla, Marmoset (87%); Rabbit (80%).
Epitope
N-Terminus
Specificity
Human EDG3 / S1P3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (6 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SIPR3 / EDG3 / S1P3
Q99500 NM_005226 NP_005217.2

Validation

SIPR3 / EDG3 / S1P3 Antibody - Prostate, Carcinoma
Prostate, Carcinoma
Prostate, Carcinoma

SIPR3 / EDG3 / S1P3 Antibody - Ovary, carcinoma
Ovary, carcinoma
Ovary, carcinoma

SIPR3 / EDG3 / S1P3 Antibody - Anti-EDG3 / S1P3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-EDG3 / S1P3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-EDG3 / S1P3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ SIPR3 / EDG3 / S1P3 Antibody (N-Terminus) for IHC LS-A1030 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/27/2021