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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-B4850-50 50 µl (1 mg/ml) $425 
PLIN2 / ADFP / Adipophilin Antibody - Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PLIN2 / ADFP / Adipophilin Antibody - Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PLIN2 / ADFP / Adipophilin Antibody - Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PLIN2 / ADFP / Adipophilin Antibody - Sample (30 ug of whole cell lysate). A: Hep G2. 10% SDS PAGE. ADFP antibody diluted at 1:1000.
PLIN2 / ADFP / Adipophilin Antibody - Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PLIN2 / ADFP / Adipophilin Antibody - Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PLIN2 / ADFP / Adipophilin Antibody - Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PLIN2 / ADFP / Adipophilin Antibody - Sample (30 ug of whole cell lysate). A: Hep G2. 10% SDS PAGE. ADFP antibody diluted at 1:1000.
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PathPlus™ Polyclonal Rabbit anti‑Human PLIN2 / ADFP / Adipophilin Antibody (IHC, WB) LS‑B4850

PathPlus™ Polyclonal Rabbit anti‑Human PLIN2 / ADFP / Adipophilin Antibody (IHC, WB) LS‑B4850

Note: This antibody replaces LS-C109437
Antibody:
PLIN2 / ADFP / Adipophilin Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425
LS-B4850-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
PLIN2 / ADFP / Adipophilin Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
PLIN2 (ADFP, Adipophilin) belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in the development and maintenance of adipose tissue. It is found in the cytoplasm and membrane of a wide range of cultured cell lines and tissues, including fibroblasts, endothelial and epithelial cells, lactating mammary glands, the adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis. Higher levels of PLIN 2 are associated with diabetes, atherosclerosis, sarcopenia, cardiovascular diseases, atherosclerosis, as well as lung, colorectal and Burkitt cancer. In clear cell renal cell carcinoma, high levels of PLIN2 are associated with survival and it is a potential prognostic marker for the disease. In immunohistochemistry, it is considered a useful marker of cytoplasmic lipids, sebocytes, and lipid accumulation, and can be used to identify sebaceous lesions and carcinomas. References: Journal of Lipid Research. 1997. 38 (11): 2249–63, PMID: 9392423; Trends Endocrinol Metab. 2016 Dec;27(12):893-903, PMID: 27659144; Intl J Clin Exp Med. 2014. 7 (4): 1190–6, PMID: 24955208; Int J Oncol. 2018 Jul; 53(1): 137–147, PMID: 29749470
Target
Human PLIN2 / ADFP / Adipophilin
Synonyms
PLIN2 | Adipophilin | ADFP | ADRP | Perilipin 2 | Perilipin-2 | Adipose differentiation-related protein
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 28 and 281 of Human ADFP.
Specificity
Human ADFP. Predicted cross-reactivity based on amino acid sequence homology: mouse (82%), bovine (86%), pig (87%).
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Western blot (1:500 - 1:3000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
0.1 M Tris-glycine, pH 7, 10% Glycerol, 0.01% Thimerosal
Storage
Keep as concentrated solution. For short term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PLIN2 / ADFP / Adipophilin
Q99541 NM_001122 NP_001113.2

Validation

PLIN2 / ADFP / Adipophilin Antibody - Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

PLIN2 / ADFP / Adipophilin Antibody - Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

PLIN2 / ADFP / Adipophilin Antibody - Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

LSBio Ratings

PathPlus™ PLIN2 / ADFP / Adipophilin Antibody for IHC, WB/Western LS-B4850 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (5)

Publications (2)

Effect of Maternal Obesity on Placental Lipid Metabolism. Calabuig-Navarro V, Haghiac M, Minium J, Glazebrook P, Ranasinghe GC, Hoppel C, Hauguel de-Mouzon S, Catalano P, O'Tierney-Ginn P. Endocrinology. 2017 August;158:2543-2555.

Inhibition of ß-Catenin Signaling in the Skin Rescues Cutaneous Adipogenesis in Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial of C-82. Lafyatis R, Mantero JC, Gordon J, Kishore N, Carns M, Dittrich H, Spiera R, Simms RW, Varga J. The Journal of investigative dermatology. 2017 December;137:2473-2483.

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 1/21/2021