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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-A1854-50 50 µg (1 mg/ml) $425 
OR51E1 Antibody - Brain, Amygdala, neurons and glia
OR51E1 Antibody - Brain, glioblastoma
OR51E1 Antibody - Brain, Alzheimer's disease senile plaque
OR51E1 Antibody - Anti-OR51E1 antibody IHC of human prostate, glands. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
OR51E1 Antibody - Anti-OR51E1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
OR51E1 Antibody - Anti-OR51E1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
OR51E1 Antibody - Brain, Amygdala, neurons and glia
OR51E1 Antibody - Brain, glioblastoma
OR51E1 Antibody - Brain, Alzheimer's disease senile plaque
OR51E1 Antibody - Anti-OR51E1 antibody IHC of human prostate, glands. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
OR51E1 Antibody - Anti-OR51E1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
OR51E1 Antibody - Anti-OR51E1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human OR51E1 Antibody (C‑Terminus, IHC) LS‑A1854

PathPlus™ Polyclonal Rabbit anti‑Human OR51E1 Antibody (C‑Terminus, IHC) LS‑A1854

Antibody:
OR51E1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425
LS-A1854-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
OR51E1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. OR51E1 has been shown to be expressed in enteroendocrine cells in the intestine, modulated by intestinal microbiota, as well as mediating GLP-1 secretion. References: https://doi.org/10.1371/journal.pone.0129501; Journal of the Endocrine Society, Volume 2, Issue 11, November 2018, Pages 1251–1258
Target
Human OR51E1
Synonyms
OR51E1 | D-GPCR | Olfactory receptor OR11-15 | OR51E1P | OR52A3P | PSGR2 | Olfactory receptor 51E1 | Olfactory receptor 52A3 | POGR | G-protein coupled receptor 164 | GPR136 | GPR164
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from C-Terminus of human OR51E1. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (95%); Gibbon, Galago (89%); Marmoset, Panda (84%).
Blocking Peptide
LS-E28417 - Liquid - 50 µg 1 mg/ml - $145.00
Immunizing peptide used to generate LS-A1854. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human OR51E1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (21 - 32 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About OR51E1
Q8TCB6 NM_152430 NP_689643.2

Validation

OR51E1 Antibody - Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia

OR51E1 Antibody - Brain, glioblastoma
Brain, glioblastoma
Brain, glioblastoma

OR51E1 Antibody - Brain, Alzheimer's disease senile plaque
Brain, Alzheimer's disease senile plaque
Brain, Alzheimer's disease senile plaque

OR51E1 Antibody - Anti-OR51E1 antibody IHC of human prostate, glands. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-OR51E1 antibody IHC of human prostate, glands. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-OR51E1 antibody IHC of human prostate, glands. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

OR51E1 Antibody - Anti-OR51E1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-OR51E1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-OR51E1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

OR51E1 Antibody - Anti-OR51E1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-OR51E1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-OR51E1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ OR51E1 Antibody (C-Terminus) for IHC LS-A1854 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (5)

Publications (2)

Olfactory receptor 51E1 as a novel target for diagnosis in somatostatin receptor-negative lung carcinoids. Giandomenico V, Cui T, Grimelius L, Öberg K, Pelosi G, Tsolakis AV. Journal of molecular endocrinology. 2013 51:277-86. (IHC; Human)

Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas. Cui T, Tsolakis AV, Li SC, Cunningham JL, Lind T, Öberg K, Giandomenico V. European journal of endocrinology / European Federation of Endocrine Societies. 2013 168:253-61. (IHC; Human)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/24/2020