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| Catalog Number | Size | Price |
|---|---|---|
| LS-A2516-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human NR2E1 / TLX Antibody (N‑Terminus, IHC) LS‑A2516
PathPlus™ Polyclonal Rabbit anti‑Human NR2E1 / TLX Antibody (N‑Terminus, IHC) LS‑A2516
Note: This antibody replaces LS-C73797
Antibody:
NR2E1 / TLX Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bat, Bovine, Dog, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
NR2E1 / TLX Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bat, Bovine, Dog, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acic receptor (RAR) regulation in retinal cells.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human NR2E1 / TLX
Synonyms
NR2E1 | HTll | Tailless homolog | Tailless | TLX | TLL | Nuclear receptor TLX | Protein tailless homolog | Tailes-related receptor | XTLL
Host
Rabbit
Reactivity
Human, Monkey, Bat, Bovine, Dog, Horse, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Hamster, Chicken, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 15 amino acid peptide from a N-Terminus of human NR2E1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Baboon, Monkey, Galago, Marmoset, Shrew, Bat, Bovine, Dog, Elephant, Panda, Rabbit, Horse, Pig, Opossum, Armadillo (100%); Mouse, Rat, Hamster, Sparrow, Chicken, Platypus, Lizard, Xenopus, Medaka, Pufferfish, Zebrafish, Stickleback (93%).
Epitope
N-Terminus
Specificity
Human NR2E1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (5.5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About NR2E1 / TLX
Validation
Colon, Carcinoma
Colon, Carcinoma
Lung, Small Cell Carcinoma
Lung, Small Cell Carcinoma
Prostate, Carcinoma
Prostate, Carcinoma
Anti-NR2E1 / TLX antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR2E1 / TLX antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR2E1 / TLX antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR2E1 / TLX antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR2E1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR2E1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ NR2E1 / TLX Antibody (N-Terminus) for IHC LS-A2516 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot
Reactivity:
Mouse
Range:
78-5000 pg/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
