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Catalog Number Size Price
LS-A7305-50 50 µg (1 mg/ml) $460 
NEK6 Antibody - Anti-NEK6 antibody IHC of human brain, Purkinje neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
NEK6 Antibody - Colon, Carcinoma
NEK6 Antibody - Pancreas, Carcinoma
NEK6 Antibody - Pancreas, Carcinoma
NEK6 Antibody - Anti-NEK6 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
NEK6 Antibody - Breast, Carcinoma
NEK6 Antibody - Anti-NEK6 antibody IHC of human brain, Purkinje neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
NEK6 Antibody - Colon, Carcinoma
NEK6 Antibody - Pancreas, Carcinoma
NEK6 Antibody - Pancreas, Carcinoma
NEK6 Antibody - Anti-NEK6 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
NEK6 Antibody - Breast, Carcinoma
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PathPlus™ Polyclonal Rabbit anti‑Human NEK6 Antibody (C‑Terminus, IHC) LS‑A7305

PathPlus™ Polyclonal Rabbit anti‑Human NEK6 Antibody (C‑Terminus, IHC) LS‑A7305

Antibody:
NEK6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-A7305-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
NEK6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
NEK6 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain. The protein is believed to regulate chromatin condensation in mammalian cells via phosphorylation of histones H1 and H3, and it has been shown to phosphorylate ribosomal S6 protein kinase (S6K1) and serum and glucocorticoid induced protein kinase (SGK1), which regulate diverse cellular processes. The protein also has been shown to bind NEK9, another NIMA-related kinase which regulates chromosome alignment and segregation. At least three mRNA transcripts have been identified, 1.6-, 2.6-, and 9.5-kb. The NEK6 gene is localized to 9q33-34, a region at which the loss of heterozygosity is associated with transitional cell carcinomas. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human NEK6
Synonyms
NEK6 | NIMA-related kinase 6 | Protein kinase SID6-1512 | NimA-related protein kinase 6 | SID6-1512
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide near C-Terminus of human NEK6. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Elephant, Panda, Dog, Bat, Rabbit, Horse, Xenopus (89%); Pig, Opossum, Turkey, Chicken (83%).
Epitope
C-Terminus
Specificity
Human NEK6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NEK7 (61%).
Applications
  • IHC
  • IHC - Paraffin (13 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About NEK6
Q9HC98 NM_014397 NP_055212.2

Validation

NEK6 Antibody - Anti-NEK6 antibody IHC of human brain, Purkinje neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NEK6 antibody IHC of human brain, Purkinje neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NEK6 antibody IHC of human brain, Purkinje neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NEK6 Antibody - Colon, Carcinoma
Colon, Carcinoma
Colon, Carcinoma

NEK6 Antibody - Pancreas, Carcinoma
Pancreas, Carcinoma
Pancreas, Carcinoma

NEK6 Antibody - Pancreas, Carcinoma
Pancreas, Carcinoma
Pancreas, Carcinoma

NEK6 Antibody - Anti-NEK6 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NEK6 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NEK6 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NEK6 Antibody - Breast, Carcinoma
Breast, Carcinoma
Breast, Carcinoma

LSBio Ratings

PathPlus™ NEK6 Antibody (C-Terminus) for IHC LS-A7305 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/19/2021