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Catalog Number Size Price
LS-B5173-0.1 0.1 ml $595 
MME / CD10 Antibody - Anti-CD10 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

PathPlus™ Monoclonal Mouse anti‑Human MME / CD10 Antibody (clone 56C6, IHC) LS‑B5173

PathPlus™ Monoclonal Mouse anti‑Human MME / CD10 Antibody (clone 56C6, IHC) LS‑B5173

Note: This antibody replaces LS-C88409
Antibody:
MME / CD10 Mouse anti-Human Monoclonal (56C6) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$595
LS-B5173-0.1
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
MME / CD10 Mouse anti-Human Monoclonal (56C6) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
CD10 (Neprilysin, MME, CALLA) is a membrane-bound, zinc-dependent metalloprotease that functions to inactivate glucagon, oxytocin, bradykinin and other peptide hormones. It also degrades and thus regulates amyloid beta peptide. In immunohistochemistry, CD10 acts as a marker for acute lymphoblastic leukemias, lymphoblastic lymphomas, Burkitt’s lymphoma, and CML. CD10 shows membranous staining and is positive in tonsil germinal center B-cells and neutrophils. In cancer, it is positive in follicular lymphomas, Burkitt's lymphomas and leukemias, precursor B-cell lymphomas, renal clear cell carcinomas, and endometrial stromal sarcomas. References: Nat Med. 2000 Feb;6(2):143-50, PMID: 10655101; Med Hypotheses. 2005;65(3):498-500, PMID: 15921860; Acta Crystallogr D Biol Crystallogr. 2004 Feb;60(Pt 2):392-6. Epub 2004 Jan 23, PMID: 14747736
Target
Human MME / CD10
Synonyms
MME | Atriopeptidase | CALLA | CD10 | EPN | Membrane metallo-endopeptidase | NEP | Neprilysin | Neutral endopeptidase | Neutral endopeptidase 24.11 | CD10 antigen | Enkephalinase | Neprylisin | SFE | Skin fibroblast elastase
Host
Mouse
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
56C6
Conjugations
Unconjugated
Modifications
Unmodified
Immunogen
Recombinant external domain of CD10 protein.
Specificity
Extracellular
Applications
  • IHC
  • IHC - Paraffin (1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
Tissue Culture Supernatant, 0.09% Sodium Azide
Storage
Stable for 2 years when stored at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MME / CD10
P08473 NM_000902 NP_000893.2

Validation

MME / CD10 Antibody - Anti-CD10 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-CD10 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-CD10 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

LSBio Ratings

PathPlus™ MME / CD10 Antibody (clone 56C6) for IHC LS-B5173 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/23/2022