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| Catalog Number | Size | Price |
|---|---|---|
| LS-A7412-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human MINK1 / MINK Antibody (Internal, IHC) LS‑A7412
PathPlus™ Polyclonal Rabbit anti‑Human MINK1 / MINK Antibody (Internal, IHC) LS‑A7412
Antibody:
MINK1 / MINK Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Horse, Pig
Format:
Unconjugated, Unmodified
Overview
Antibody:
MINK1 / MINK Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Horse, Pig
Format:
Unconjugated, Unmodified
Specifications
Description
Misshapen-like kinase 1 (MINK1) is required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. MINK1 can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. It has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1. MINK1 is involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human MINK1 / MINK
Synonyms
MINK1 | HMINKbeta | GCK family kinase MiNK | MAP4K6 | Misshapen/NIK-related kinase | MinK | Mink 1 | Misshapen/NIKs-related kinase | HMINK | MEKKK 6 | Mink 2 | B55 | ZC3 | MEK kinase kinase 6 | Misshapen-like kinase 1 | YSK2
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Horse, Pig
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from internal region of human MINK1 / MAP4K6. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Bat, Horse, Pig (100%); Opossum (94%); Xenopus (83%).
Epitope
Internal
Specificity
Human MINK1 / MAP4K6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (7 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MINK1 / MINK
Validation
Skin, Melanoma
Skin, Melanoma
Brain, substantia nigra
Brain, substantia nigra
Brain, Hypothalamus
Brain, Hypothalamus
Anti-MINK1 / MAP4K6 antibody IHC of rat hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MINK1 / MAP4K6 antibody IHC of rat hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MINK1 / MINK antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MINK1 / MINK antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MINK1 / MINK antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MINK1 / MINK antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MINK1 / MAP4K6 antibody IHC of human hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MINK1 / MAP4K6 antibody IHC of human hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ MINK1 / MINK Antibody (Internal) for IHC LS-A7412 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Hamster, Horse, Pig
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Mouse
Applications:
Western blot, Immunoprecipitation
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat, Bovine
Applications:
IHC, IHC - Paraffin, Western blot
Source:
E. coli
Tag:
His
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
