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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16949-50 | 50 µl (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human LSP1 Antibody (IHC, WB) LS‑B16949
PathPlus™ Polyclonal Rabbit anti‑Human LSP1 Antibody (IHC, WB) LS‑B16949
Note: This antibody replaces LS-C667891
Antibody:
LSP1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
LSP1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
LSP1 is an intracellular F-actin binding protein expressed in lymphocytes, neutrophils, macrophages, and endothelium. It regulates neutrophil motility, adhesion to fibrinogen matrix proteins, transendothelial migration, and actomyosin contractility in macrophages. Some inherited polymorphisms in LSP1 are associated with increased risk for breast cancer. In immunohistochemistry, LSP1 has membranous and cytoplasmic positivity in immune cells.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; Int J Clin Exp Pathol. 2015; 8(5): 5798–5802, PMID: 26191300; Nat Commun 9, 515 (2018), DOI:10.1038/s41467-018-02904-x
Target
Human LSP1
Synonyms
LSP1 | 47 kDa actin-binding protein | 47 kDa actin binding protein | 52 kDa phosphoprotein | Leukocyte-specific protein 1 | Lymphocyte-specific protein 1 | Pp52 | WP34
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
This antibody is purified by immunogen affinity chromatography
Modifications
Unmodified
Immunogen
Recombinant full length protein of human LSP1
Specificity
Recognizes endogenous levels of LSP1 protein.
Applications
- IHC - Paraffin (1:100)
- Western blot (1:500 - 1:2000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Storage
Upon delivery, aliquot and store at -20°C for 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About LSP1
Validation
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ LSP1 Antibody for IHC, WB/Western LS-B16949 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC - Paraffin, Western blot
Species:
Human, Monkey, Mouse, Rat, Dog, Hamster
Applications:
IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
IHC - Paraffin, Western blot
Species:
Human, Monkey, Mouse, Rat, Dog, Hamster
Applications:
IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Reactivity:
Human
Range:
0.23-15 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
