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| Catalog Number | Size | Price |
|---|---|---|
| LS-A212-50 | 50 µg (1 mg/ml) | $440 |
1 of 2
2 of 2
PathPlus™ Polyclonal Rabbit anti‑Human LPAR1 / LPA1 / EDG2 Antibody (N‑Terminus, IHC) LS‑A212
PathPlus™ Polyclonal Rabbit anti‑Human LPAR1 / LPA1 / EDG2 Antibody (N‑Terminus, IHC) LS‑A212
Antibody:
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
Lysophosphatidic acid receptor 1 (LPAR1) is a member of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human LPAR1 / LPA1 / EDG2
Synonyms
LPAR1 | EDG-2 | EDG2 | Gpcr26 | Rec.1.3 | Vzg-1 | Ventricular zone gene 1 | LPA receptor 1 | LPA-1 | LPA1 | Mrec1.3 | VZG1
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Sheep, Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 15 amino acid peptide from N-Terminus extracellular domain of human EDG2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant (100%); Mouse, Rat, Sheep, Dog, Bovine, Bat, Hamster, Panda, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus (93%); Xenopus, Pufferfish, Zebrafish (87%).
Epitope
N-Terminus
Specificity
Human EDG2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DDX60 (53%), ACER3 (47%).
Applications
- IHC
- IHC - Paraffin (1 - 2 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About LPAR1 / LPA1 / EDG2
Validation
Brain, Glioblastoma
Brain, Glioblastoma
Skin, Melanoma
Skin, Melanoma
See More About...
LSBio Ratings
PathPlus™ LPAR1 / LPA1 / EDG2 Antibody (N-Terminus) for IHC LS-A212 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Sheep, Chicken, Xenopus
Applications:
IHC, IHC - Paraffin, ICC, Western blot
Species:
Human, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
Immunofluorescence, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
