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Catalog Number Size Price
LS-B11232-50 50 µg (0.5 mg/ml) $440 
KRT18 / CK18 / Cytokeratin 18 Antibody - Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
KRT18 / CK18 / Cytokeratin 18 Antibody - Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
KRT18 / CK18 / Cytokeratin 18 Antibody - Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
KRT18 / CK18 / Cytokeratin 18 Antibody - Goat Anti-keratin 18 Antibody (0.1µg/ml) staining of Pig Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescencence
KRT18 / CK18 / Cytokeratin 18 Antibody - KRT18 antibody (0.1 ug/ml) staining of HeLa lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
KRT18 / CK18 / Cytokeratin 18 Antibody - Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
KRT18 / CK18 / Cytokeratin 18 Antibody - Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
KRT18 / CK18 / Cytokeratin 18 Antibody - Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
KRT18 / CK18 / Cytokeratin 18 Antibody - Goat Anti-keratin 18 Antibody (0.1µg/ml) staining of Pig Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescencence
KRT18 / CK18 / Cytokeratin 18 Antibody - KRT18 antibody (0.1 ug/ml) staining of HeLa lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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PathPlus™ Polyclonal Goat anti‑Human KRT18 / CK18 / Cytokeratin 18 Antibody (aa200‑300, IHC, WB) LS‑B11232

PathPlus™ Polyclonal Goat anti‑Human KRT18 / CK18 / Cytokeratin 18 Antibody (aa200‑300, IHC, WB) LS‑B11232

Note: This antibody replaces LS-C205040
Antibody:
KRT18 / CK18 / Cytokeratin 18 Goat anti-Human Polyclonal (aa200-300) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Xenopus
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B11232-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
KRT18 / CK18 / Cytokeratin 18 Goat anti-Human Polyclonal (aa200-300) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Xenopus
Format:
Unconjugated, Unmodified

Specifications

Description
Cytokeratin 18 (KRT18, CK18) is a Type I intermediate filament chain keratin that is expressed in simple non-stratified epithelial tissues, eccrine glands, trophoblasts and endothelia of veins and lymphatics. Along with KRT8, KRT18 protects the liver from stress-induced injury and apoptosis. Mutations in this gene have been linked to cryptogenic cirrhosis and a variety of liver diseases, particularly after alcohol or viral infections. It is also a serum marker for breast carcinoma and late stage bladder carcinoma. It is positive in a variety of adenocarcinomas and hepatocellular carcinoma, and is generally negative in squamous cell carcinomas. References: Gastroenterol 2005 129(3):885; Hepatology 2007 46(5):1639; Am J Clin Path 123(1):66; Clin Biochem 35(4):327; Histopath 1993 23(1):45
Target
Human KRT18 / CK18 / Cytokeratin 18
Synonyms
KRT18 | CK-18 | Cytokeratin 18 | Cytokeratin-18 | K18 | Keratin 18 | CYK18 | Keratin-18
Host
Goat
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Xenopus (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
A synthetic peptide of human KRT18
Epitope
aa200-300
Specificity
Human KRT18 / Cytokeratin 18. Reported variants represent identical protein: NP_000215.1, NP_954657.1.
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.1 - 0.3 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx 48kD band observed in lysates of cell lines A431, HeLa, MCF7 (calculated MW of 48.1kD according to NP_000215.1). Recommended concentration: 0.1-0.3 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KRT18 / CK18 / Cytokeratin 18
P05783 NM_000224 NP_000215.1

Validation

KRT18 / CK18 / Cytokeratin 18 Antibody - Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

KRT18 / CK18 / Cytokeratin 18 Antibody - Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

KRT18 / CK18 / Cytokeratin 18 Antibody - Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LSBio Ratings

PathPlus™ KRT18 / CK18 / Cytokeratin 18 Antibody (aa200-300) for IHC, WB/Western LS-B11232 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/23/2022