Products
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, Proforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-B573-0.05 0.05 mg (1 mg/ml) $440 
IL23A / IL-23 p19 Antibody - Anti-IL-23 p19 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
IL23A / IL-23 p19 Antibody - Anti-IL-23 p19 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
IL23A / IL-23 p19 Antibody - Immunofluorescence of IL-23 in Mouse Pancreas cells with IL-23 antibody at 20 ug/ml.
IL23A / IL-23 p19 Antibody - Western blot of IL-23 in mouse pancreas tissue lysate with IL-23 antibody at (A) 1 and (B) 2 ug/ml.
IL23A / IL-23 p19 Antibody - Anti-IL-23 p19 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
IL23A / IL-23 p19 Antibody - Anti-IL-23 p19 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
IL23A / IL-23 p19 Antibody - Immunofluorescence of IL-23 in Mouse Pancreas cells with IL-23 antibody at 20 ug/ml.
IL23A / IL-23 p19 Antibody - Western blot of IL-23 in mouse pancreas tissue lysate with IL-23 antibody at (A) 1 and (B) 2 ug/ml.
1 of 4
2 of 4
3 of 4
4 of 4

PathPlus™ Polyclonal Rabbit anti‑Human IL23A / IL‑23 p19 Antibody (IHC, IF, WB) LS‑B573

PathPlus™ Polyclonal Rabbit anti‑Human IL23A / IL‑23 p19 Antibody (IHC, IF, WB) LS‑B573

Note: This antibody replaces LS-C19594, LS-C42488, LS-C37066
Antibody:
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B573-0.05
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
IL23A (Interleukin-23 subunut alpha) is a cytokine that functions in the inflammatory and immune responses to infection and also promotes angiogenesis. Loss of IL23A leads to inflammatory bowel disease and experimental autoimmune encephalomyelitis in mice. It is also implicated in the pathogenesis of immune and inflammatory diseases such as spondyloarthritis and psoriatic arthritis. Inherited mutation and separately upregulation in IL23A are implicated in multiple sclerosis and immune inflammatory disease. In immunohistochemistry, IL23A has cytoplasmic positivity in immune cells and most tissues throughout the body. References: Current Opinion in Immunology. 18 (6): 670–5. doi:10.1016/j.coi.2006.09.008, PMID: 17010592; Nature. 442 (7101): 461–5, PMID: 16688182; Arthritis Rheumatol. 2014 Feb;66(2):231-41, PMID: 24504793; International Journal of Rheumatology. 2012 (539683), DOI: 10.1155/2012/539683; Aging (Albany NY). 2016 Nov; 8(11): 2734–2744; Brain. 2007. 130 (2): 490–501, DOI: 10.1093/brain/awl273;
Target
Human IL23A / IL-23 p19
Synonyms
IL23A | IL-23 subunit alpha | IL-23A | Interleukin 23 p19 subunit | Interleukin-23 subunit alpha | IL23P19 | Interleukin-23 subunit p19 | p19 | SGRF | IL-23 | IL-23 p19 | IL-23-A | IL-23p19
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Peptide Column Affinity Chromatography
Modifications
Unmodified
Immunogen
A 17 AA synthetic peptide near the N-Terminus of human IL-23. The immunogen is located within aa 40-90 of IL-23.
Applications
  • IHC (2 µg/ml)
  • IHC - Paraffin (2.5 µg/ml)
  • Immunofluorescence (20 µg/ml)
  • Western blot (0.25 - 2 µg/ml)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
IL-23 antibody can be used for the detection of IL-23 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2 ug/mL. For immunofluorescence start at 20 ug/mL. Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Western Blot: Predicted: 21 kDa Observed: 23 kDa
Presentation
PBS containing 0.02% Sodium Azide
Storage
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About IL23A / IL-23 p19
Q9NPF7 NM_016584 NP_057668.1

Validation

IL23A / IL-23 p19 Antibody - Anti-IL-23 p19 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-IL-23 p19 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-IL-23 p19 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IL23A / IL-23 p19 Antibody - Anti-IL-23 p19 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-IL-23 p19 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-IL-23 p19 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LSBio Ratings

PathPlus™ IL23A / IL-23 p19 Antibody for IHC, IF/Immunofluorescence, WB/Western, ELISA LS-B573 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation. Li H, Yao Q, Mariscal AG, Wu X, Hülse J, Pedersen E, Helin K, Waisman A, Vinkel C, Thomsen SF, Avgustinova A, Benitah SA, Lovato P, Norsgaard H, Mortensen MS, Veng L, Rozell B, Brakebusch C. Nature communications. 2018 April;9:1420. (Human)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/19/2021