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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-B6043-100 100 µg (1 mg/ml) $670 
HTR1A / 5-HT1A Receptor Antibody - Anti-5HT1A Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

PathPlus™ Monoclonal Mouse anti‑Rat HTR1A / 5‑HT1A Receptor Antibody (clone 19A9.2, IHC, WB) LS‑B6043

PathPlus™ Monoclonal Mouse anti‑Rat HTR1A / 5‑HT1A Receptor Antibody (clone 19A9.2, IHC, WB) LS‑B6043

Note: This antibody replaces LS-C132053
Antibody:
HTR1A / 5-HT1A Receptor Mouse anti-Rat Monoclonal (19A9.2) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Rat, Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$670
LS-B6043-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
HTR1A / 5-HT1A Receptor Mouse anti-Rat Monoclonal (19A9.2) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Rat, Human
Format:
Unconjugated, Unmodified

Specifications

Description
HTR1A is the G-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a membrane receptor for various drugs and psychoactive substances, and plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain. It is involved in affecting neural activity, mood and behavior, as well as the response to anxiogenic stimuli. The receptor is expressed in various regions of the brain, in lymphoid tissues, and activated T cells. References: J. Neurochem. 107 (2): 488–96, PMID: 18761712; Hum Brain Mapp. 2018 Feb;39(2):1043-1055, PMID: 29323797
Target
Rat HTR1A / 5-HT1A Receptor
Synonyms
HTR1A | 5-HT-1A | 5HT1a | 5-HT1a receptor | 5HT1ar | 5HT1A receptor | 5-HT1A | ADRBRL1 | ADRB2RL1 | PFMCD | Serotonin 5-HT-1a receptor | Serotonin type 1a receptor | Serotonergic type 1A receptor | G-21 | Serotonin 1a receptor | Serotonin receptor 1A
Host
Mouse
Reactivity
Rat, Human (tested or 100% immunogen sequence identity)
Clonality
IgM,k Monoclonal
Clone
19A9.2
Conjugations
Unconjugated
Purification
Ion exchange chromatography
Modifications
Unmodified
Immunogen
Linear peptide corresponding to rat Serotonin receptor 1A (KLH).
Specificity
Recognizes rat Serotonin receptor 1A. Species cross-reactivity: human.
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Western blot (0.5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 0.5 ug/ml detects Serotonin receptor 1A on 10 ug of rat brain tissue lysate. Immunohistochemistry: 1:400 detects Serotonin receptor 1A in normal human brain tissue.
Presentation
PBS, 0.05% Sodium Azide
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HTR1A / 5-HT1A Receptor
P08908 NM_000524 NP_000515.2

Validation

HTR1A / 5-HT1A Receptor Antibody - Anti-5HT1A Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-5HT1A Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-5HT1A Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

LSBio Ratings

PathPlus™ HTR1A / 5-HT1A Receptor Antibody (clone 19A9.2) for IHC, WB/Western LS-B6043 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/3/2020