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| Catalog Number | Size | Price |
|---|---|---|
| LS-A830-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human GRPR Antibody (Extracellular Domain, IHC, WB) LS‑A830
PathPlus™ Polyclonal Rabbit anti‑Human GRPR Antibody (Extracellular Domain, IHC, WB) LS‑A830
Antibody:
GRPR Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Monkey, Bat, Dog, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
GRPR Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Monkey, Bat, Dog, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
Gastrin-releasing peptide receptor (GRPR) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRPR are mediated through the gastrin-releasing peptide receptor. GRPR is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GRPR
Synonyms
GRPR | GRP-R | Bombesin BB2 receptor | GRP receptor | Grp/bombesin receptor
Host
Rabbit
Reactivity
Human, Monkey, Bat, Dog, Horse, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from 2nd extracellular domain of human GRPR. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Dog, Bat, Horse, Rabbit, Pig (100%); Bovine (94%); Mouse, Rat, Hamster (83%).
Epitope
Extracellular Domain
Specificity
Human GRPR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (4 µg/ml)
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GRPR
Validation
Stomach
Stomach
Brain Cerebellum Purkinje Neurons
Brain Cerebellum Purkinje Neurons
Anti-GRPR antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRPR antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRPR antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRPR antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRPR antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRPR antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ GRPR Antibody (Extracellular Domain) for IHC, WB/Western LS-A830 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Pig
Applications:
IHC, IHC - Paraffin, ICC
Species:
Human, Mouse, Rat
Applications:
IHC, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/15/2024
Date Requested: 4/15/2024
