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Catalog Number Size Price
LS-A45-50 50 µg (1 mg/ml) $440 
GPR183 / EBI2 Antibody - Brain, Cortex neurons
GPR183 / EBI2 Antibody - Anti-GPR183 / EBI2 antibody IHC of human peripheral blood leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPR183 / EBI2 Antibody - Ovary, Carcinoma
GPR183 / EBI2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
GPR183 / EBI2 Antibody - Colon, adenocarcinoma
GPR183 / EBI2 Antibody - Brain, Cortex neurons
GPR183 / EBI2 Antibody - Anti-GPR183 / EBI2 antibody IHC of human peripheral blood leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPR183 / EBI2 Antibody - Ovary, Carcinoma
GPR183 / EBI2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
GPR183 / EBI2 Antibody - Colon, adenocarcinoma
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PathPlus™ Polyclonal Rabbit anti‑Human GPR183 / EBI2 Antibody (Extracellular Domain, IHC) LS‑A45

PathPlus™ Polyclonal Rabbit anti‑Human GPR183 / EBI2 Antibody (Extracellular Domain, IHC) LS‑A45

Antibody:
GPR183 / EBI2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$440
LS-A45-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
GPR183 / EBI2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
G protein-coupled receptor 183 (GPR183) is a receptor for oxysterol 7-alpha, 25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols. Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses. GPR183 promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). GPR183 signals constitutively through G(i)-alpha, but not through G(s)-alpha or G(q)-alpha, and it also signals constitutively via MAPK1/3 (ERK1/2). References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GPR183 / EBI2
Synonyms
GPR183 | EBI 2 | EBI2 | EBV-induced gene 2 | G protein-coupled receptor 183 | G-protein coupled receptor 183
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Predicted
Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from 2nd extracellular domain of human GPR183 / EBI2. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%); Bovine (94%); Hamster, Panda, Bat, Dog, Pig (89%); Marmoset, Horse (83%).
Epitope
Extracellular Domain
Specificity
Human GPR183 / EBI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NBEA (39%).
Applications
  • IHC
  • IHC - Paraffin (3 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GPR183 / EBI2
P32249 NM_004951 NP_004942.1

Validation

GPR183 / EBI2 Antibody - Brain, Cortex neurons
Brain, Cortex neurons
Brain, Cortex neurons

GPR183 / EBI2 Antibody - Anti-GPR183 / EBI2 antibody IHC of human peripheral blood leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR183 / EBI2 antibody IHC of human peripheral blood leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR183 / EBI2 antibody IHC of human peripheral blood leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPR183 / EBI2 Antibody - Ovary, Carcinoma
Ovary, Carcinoma
Ovary, Carcinoma

GPR183 / EBI2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

GPR183 / EBI2 Antibody - Colon, adenocarcinoma
Colon, adenocarcinoma
Colon, adenocarcinoma

LSBio Ratings

PathPlus™ GPR183 / EBI2 Antibody (Extracellular Domain) for IHC LS-A45 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/17/2021