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Catalog Number Size Price
LS-A4268-50 50 µg (1 mg/ml) $440 
GPER1 / GPR30 Antibody - Anti-GPR30 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.
GPER1 / GPR30 Antibody - Anti-GPR30 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.
GPER1 / GPR30 Antibody - Anti-GPR30 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.
GPER1 / GPR30 Antibody - Anti-GPR30 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.
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PathPlus™ Polyclonal Rabbit anti‑Human GPER1 / GPR30 Antibody (Extracellular Domain, IHC) LS‑A4268

PathPlus™ Polyclonal Rabbit anti‑Human GPER1 / GPR30 Antibody (Extracellular Domain, IHC) LS‑A4268

Note: This antibody replaces LS-C66913
Antibody:
GPER1 / GPR30 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$440
LS-A4268-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
GPER1 / GPR30 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
G-protein coupled estrogen receptor 1 (GPER1) promotes neuritogenesis in developing hippocampal neurons. It plays a role in acute neuroprotection against NMDA-induced excitotoxic neuronal death and increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons. GPER1 inhibits mature adipocyte differentiation and lipid accumulation, and is involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells. It also functions as a receptor for aldosterone, mediating rapid regulation of vascular contractibility through the PI3K/ERK signaling pathway. Finally, it is implicated in cancer progression. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GPER1 / GPR30
Synonyms
GPER1 | CMKRL2 | CEPR | FEG-1 | G-protein coupled receptor 30 | G protein-coupled receptor 30 | GPCR-Br | GPER | Heptahelix receptor | LERGU | LyGPR | MER | GPR30 | IL8-related receptor DRY12 | LERGU2 | Chemokine receptor-like 2 | DRY12 | Membrane estrogen receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR30. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%); Marmoset, Elephant (93%); Mouse, Rat, Hamster, Panda, Horse, Opossum, Platypus (87%); Dog, Bovine, Turkey, Zebra finch, Chicken (80%).
Epitope
Extracellular Domain
Specificity
Human GPR30. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (5 - 7.5 µg/ml)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GPER1 / GPR30
Q99527 NM_001505 NP_001496.1

Validation

GPER1 / GPR30 Antibody - Anti-GPR30 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.
Anti-GPR30 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.
Anti-GPR30 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.

GPER1 / GPR30 Antibody - Anti-GPR30 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.
Anti-GPR30 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.
Anti-GPR30 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.

LSBio Ratings

PathPlus™ GPER1 / GPR30 Antibody (Extracellular Domain) for IHC, ELISA LS-A4268 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/13/2022