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| Catalog Number | Size | Price |
|---|---|---|
| LS-A94-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human GPCRW / GPR18 Antibody (Extracellular Domain, IHC) LS‑A94
PathPlus™ Polyclonal Rabbit anti‑Human GPCRW / GPR18 Antibody (Extracellular Domain, IHC) LS‑A94
Antibody:
GPCRW / GPR18 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
GPCRW / GPR18 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
G protein-coupled receptor 18 (GPR18) is a receptor for N-arachidonyl glycine, abnormal cannabidiol, Resolvin D2 and endogenous lipid neurotransmitters. GPR18 is mediated by G proteins which inhibit adenylyl cyclase and may contribute to regulation of inflamattion and the immune system. In immunohistochemistry, GPR18 has cytoplasmic and membranous positivity in immune cells.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GPCRW / GPR18
Synonyms
GPR18 | GPCRW | G protein-coupled receptor 18 | NAGly receptor | G-protein coupled receptor 18 | N-arachidonyl glycine receptor
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 17 amino acid peptide from 2nd extracellular domain of human GPR18. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Horse, Rabbit (88%); Mouse, Rat, Elephant, Bat, Pig (82%).
Epitope
Extracellular Domain
Specificity
Human GPR18. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (2.5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GPCRW / GPR18
Validation
Colon, Adenocarcinoma
Colon, Adenocarcinoma
Brain Infarct Neuron and Glia
Brain Infarct Neuron and Glia
Anti-GPR18 antibody IHC of human testis, seminiferous tubule. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR18 antibody IHC of human testis, seminiferous tubule. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Ovary, carcinoma
Ovary, carcinoma
See More About...
LSBio Ratings
PathPlus™ GPCRW / GPR18 Antibody (Extracellular Domain) for IHC LS-A94 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation. Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RP, Serhan CN, Gilroy DW. JCI insight. 2018 March;3:pii: 94463. (Human)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
ICC, Immunofluorescence, Western blot, Flow Cytometry
Species:
Human, Monkey, Bat, Horse, Rabbit
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/17/2024
Date Requested: 4/17/2024
