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Catalog Number Size Price
LS-A8066-50 50 µg (1 mg/ml) $460 
GPCR6 / GPR101 Antibody - Brain, glioblastoma
GPCR6 / GPR101 Antibody - Breast, carcinoma
GPCR6 / GPR101 Antibody - Anti-GPR101 antibody IHC of human brain, hypothalamus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPCR6 / GPR101 Antibody - Brain, Glioblastoma
GPCR6 / GPR101 Antibody - Brain, glioblastoma
GPCR6 / GPR101 Antibody - Breast, carcinoma
GPCR6 / GPR101 Antibody - Anti-GPR101 antibody IHC of human brain, hypothalamus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPCR6 / GPR101 Antibody - Brain, Glioblastoma
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PathPlus™ Polyclonal Rabbit anti‑Human GPCR6 / GPR101 Antibody (Cytoplasmic Domain, IHC) LS‑A8066

PathPlus™ Polyclonal Rabbit anti‑Human GPCR6 / GPR101 Antibody (Cytoplasmic Domain, IHC) LS‑A8066

Antibody:
GPCR6 / GPR101 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-A8066-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
GPCR6 / GPR101 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
GPR101 is a G protein-coupled receptor putatively involved in growth regulation. Duplications of this gene and coinciding overexpression of GPR101 results in acromegaly and gigantism. This may be caused by downstream upregulation of hypothalamic GHRH and dysfunction of the growth hormone axis in the pituitary and hypothalamus resulting from baseline increased GPR101. In immunohistochemistry, GPR101 has membranous positivity in the hypothalamus, basal ganglia, and cerebral cortex in the central nervous system. References: N. Engl. J. Med. 371: 2363–74, PMID: 25470569; Acta Neuropathol Commun. 2016; 4: 56, PMID: 27245663
Target
Human GPCR6 / GPR101
Synonyms
GPR101 | G protein-coupled receptor 101 | GPCR6
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human GPR101. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Marmoset (94%); Orangutan (88%); Gibbon (82%).
Epitope
Cytoplasmic Domain
Specificity
Human GPR101. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (3 - 6 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GPCR6 / GPR101
Q96P66 NM_054021 NP_473362.1

Validation

GPCR6 / GPR101 Antibody - Brain, glioblastoma
Brain, glioblastoma
Brain, glioblastoma

GPCR6 / GPR101 Antibody - Breast, carcinoma
Breast, carcinoma
Breast, carcinoma

GPCR6 / GPR101 Antibody - Anti-GPR101 antibody IHC of human brain, hypothalamus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR101 antibody IHC of human brain, hypothalamus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR101 antibody IHC of human brain, hypothalamus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPCR6 / GPR101 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

LSBio Ratings

PathPlus™ GPCR6 / GPR101 Antibody (Cytoplasmic Domain) for IHC LS-A8066 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 7/23/2024