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Catalog Number Size Price
LS-A31-50 50 µg (1 mg/ml) $440 
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with CNR1 / CB1.
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with CNR1 / CB1.
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
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PathPlus™ Polyclonal Rabbit anti‑Human CNR1 / CB1 Antibody (Cytoplasmic Domain, IHC) LS‑A31

PathPlus™ Polyclonal Rabbit anti‑Human CNR1 / CB1 Antibody (Cytoplasmic Domain, IHC) LS‑A31

Antibody:
CNR1 / CB1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P, ICC
Reactivity:
Human, Monkey, Mouse, Rat, Hamster
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-A31-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
CNR1 / CB1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P, ICC
Reactivity:
Human, Monkey, Mouse, Rat, Hamster
Format:
Unconjugated, Unmodified

Specifications

Description
CNR1 (CB1, cannabinoid receptor type 1) is a G protein-coupled cannabinoid receptor that binds endocannabinoid neurotransmitters and their analogs in the brain. CNR1 functions include regulating cardiac blood supply, inhibiting neuronal excitability in the brain, regulating motor control, and reinforcing drug-seeking behavior in addiction. CNR1 is also an important modulator of anxiety and arousal in response to novel situations; loss of CNR1 has been found to lead to increased object exploration, social interaction and aggression in mice. In immunohistochemistry, CNR1 has membranous positivity in the peripheral and central nervous systems. It is also found on cells in the pituitary, thyroid and adrenal glands, on fat and muscle cells, and in the liver, retina, digestive tract, lungs and kidney. References: Abood, Mary et al. Cannabinoid receptors: CB1 receptor. IUPHAR/BPS Guide to PHARMACOLOGY. 2019, URL: www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=56; Endocrine Reviews. 27 (1): 73–100, PMID: 16306385; PLOS ONE. 6 (11): e26617, PMID: 22069458.
Target
Human CNR1 / CB1
Synonyms
CNR1 | CB-R | CB1 receptor | CB1A | CB1R | Cannabinoid receptor 1 | Cannabinoid receptor CB1 | Cannabinoid Receptor I | CB1 | CB1K5 | CANN6 | Cannabinoid receptor 1 (brain) | CNR | Cannabinoid CB(1) receptor | CB1 cannabinoid receptor | Central cannabinoid receptor
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human CNR1 / CB1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Monkey, Mouse, Rat, Shrew, Hamster, Elephant, Cat (100%).
Epitope
Cytoplasmic Domain
Specificity
Human CNR1 / CB1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (5 - 10 µg/ml)
  • ICC
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CNR1 / CB1
P21554 X54937 CAA57018.1

Validation

CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CNR1 / CB1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CNR1 / CB1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CNR1 / CB1 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CNR1 / CB1 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with CNR1 / CB1.
Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with CNR1 / CB1.
Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with CNR1 / CB1.

CNR1 / CB1 Antibody - Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-CNR1 / CB1 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.

LSBio Ratings

PathPlus™ CNR1 / CB1 Antibody (Cytoplasmic Domain) for IHC, ICC LS-A31 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


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Technical.Support@LSBio.com

Requested From: United States
Date Requested: 7/13/2024