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Catalog Number Size Price
LS-A1242-50 50 µg (1 mg/ml) $440 
CCR1 Antibody - Pancreas, adenocarcinoma
CCR1 Antibody - Colon Ulcerative colitis eosinophils
CCR1 Antibody - Brain Amygdala Neurons and Glia
CCR1 Antibody - Anti-CCR1 antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CCR1 Antibody - Anti-CCR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CCR1 Antibody - Anti-CCR1 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CCR1 Antibody - Anti-CCR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CCR1 Antibody - Pancreas, adenocarcinoma
CCR1 Antibody - Colon Ulcerative colitis eosinophils
CCR1 Antibody - Brain Amygdala Neurons and Glia
CCR1 Antibody - Anti-CCR1 antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CCR1 Antibody - Anti-CCR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CCR1 Antibody - Anti-CCR1 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CCR1 Antibody - Anti-CCR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human CCR1 Antibody (Extracellular Domain, IHC) LS‑A1242

PathPlus™ Polyclonal Rabbit anti‑Human CCR1 Antibody (Extracellular Domain, IHC) LS‑A1242

Antibody:
CCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$440
LS-A1242-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
CCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
CCR1 (C-C chemokine receptor type 1, CD191) is a member of the beta chemokine receptor family and is a GPCR (G protein-coupled receptor). Knockout studies in mice show that this gene functions in host protection from inflammatory response and is important for susceptibility to viruses and parasites. It is upregulated in macrophages and microglia during the inflammatory response and during myelination in the spinal cord of mice with autoimmune encephalomyelitis. CCR1 is a useful marker for early Alzheimer’s disease, and positivity is strongly correlated with dementia state and is found in plaque-like structures in the hippocampus and entorhinal cortex. Furthermore, CCR1 is involved in the pathogenesis of multiple myeloma and also renal diseases where it regulates myeloid cell kidney infiltration. In immunohistochemistry, CCR1 has positive membranous staining in dendritic cells, monocytes and macrophages, neutrophils, eosinophils, basophils and lymphocytes. References: Nucleic Acids Res. 2009 Jan; 37(Database issue): D32–D36, PMID: 18927115; J Neuroinflammation. 2007 May 7;4:14, PMID: 17484785; Am J Pathol 2012;180:1040, PMID: 22203055; Future Med Chem 2011;3:1889, PMID:22023033; Ann Neurol. 2003 Nov;54(5):638-46, PMID: 14595653
Target
Human CCR1
Synonyms
CCR1 | C-C chemokine receptor type 1 | CD191 | CD191 antigen | CKR-1 | CKR1 | CMKBR1 | CC-CKR-1 | CMKR1 | HM145 | MIP-1 alpha | RANTES-R | RANTES receptor | SCYAR1 | MIP-1 alpha receptor | C-C CKR-1 | CCR-1 | LD78 receptor | MIP-1alpha-R | MIP1aR
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from human CCR1. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Bovine (95%); Mouse (85%); Marmoset (80%).
Epitope
Extracellular Domain
Specificity
Human CCR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CCR1
P32246 NM_001295 NP_001286.1

Validation

CCR1 Antibody - Pancreas, adenocarcinoma
Pancreas, adenocarcinoma
Pancreas, adenocarcinoma

CCR1 Antibody - Colon Ulcerative colitis eosinophils
Colon Ulcerative colitis eosinophils
Colon Ulcerative colitis eosinophils

CCR1 Antibody - Brain Amygdala Neurons and Glia
Brain Amygdala Neurons and Glia
Brain Amygdala Neurons and Glia

CCR1 Antibody - Anti-CCR1 antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR1 antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR1 antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CCR1 Antibody - Anti-CCR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CCR1 Antibody - Anti-CCR1 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR1 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR1 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CCR1 Antibody - Anti-CCR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ CCR1 Antibody (Extracellular Domain) for IHC LS-A1242 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

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Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/27/2021