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Catalog Number Size Price
LS-A431-50 50 µg (1 mg/ml) $440 
C5AR2 / GPR77 / C5L2 Antibody - Brain, Glioblastoma
C5AR2 / GPR77 / C5L2 Antibody - Anti-C5L2 antibody IHC of human adrenal, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
C5AR2 / GPR77 / C5L2 Antibody - Brain, Amygdala
C5AR2 / GPR77 / C5L2 Antibody - Brain, Alzheimer's disease, neurofibrillary tangle
C5AR2 / GPR77 / C5L2 Antibody - Brain, Glioblastoma
C5AR2 / GPR77 / C5L2 Antibody - Anti-C5L2 antibody IHC of human adrenal, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
C5AR2 / GPR77 / C5L2 Antibody - Brain, Amygdala
C5AR2 / GPR77 / C5L2 Antibody - Brain, Alzheimer's disease, neurofibrillary tangle
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PathPlus™ Polyclonal Rabbit anti‑Human C5AR2 / GPR77 / C5L2 Antibody (Extracellular Domain, IHC) LS‑A431

PathPlus™ Polyclonal Rabbit anti‑Human C5AR2 / GPR77 / C5L2 Antibody (Extracellular Domain, IHC) LS‑A431

Antibody:
C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$440
LS-A431-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Complement component 5a receptor 2 (C5AR2) is involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. Instead C5AR2 modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. C5AR2 may be involved in coronary artery disease and in the pathogenesis of sepsis. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human C5AR2 / GPR77 / C5L2
Synonyms
C5AR2 | G-protein coupled receptor 77 | GPF77 | GPR77 | C5L2 | G protein-coupled receptor 77
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from 2nd extracellular domain of human C5L2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Bovine, Pig (89%); Panda (84%).
Epitope
Extracellular Domain
Specificity
Human C5L2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (25 - 33 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About C5AR2 / GPR77 / C5L2
Q9P296 NM_018485 NP_060955.1

Validation

C5AR2 / GPR77 / C5L2 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

C5AR2 / GPR77 / C5L2 Antibody - Anti-C5L2 antibody IHC of human adrenal, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-C5L2 antibody IHC of human adrenal, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-C5L2 antibody IHC of human adrenal, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

C5AR2 / GPR77 / C5L2 Antibody - Brain, Amygdala
Brain, Amygdala
Brain, Amygdala

C5AR2 / GPR77 / C5L2 Antibody - Brain, Alzheimer's disease, neurofibrillary tangle
Brain, Alzheimer's disease, neurofibrillary tangle
Brain, Alzheimer's disease, neurofibrillary tangle

LSBio Ratings

PathPlus™ C5AR2 / GPR77 / C5L2 Antibody (Extracellular Domain) for IHC LS-A431 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/16/2021