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Catalog Number Size Price
LS-A797-50 50 µg (1 mg/ml) $440 
BDKRB2/Bradykinin B2 Receptor Antibody - Heart, Myocardial infarct
BDKRB2/Bradykinin B2 Receptor Antibody - Artery, Tunica media
BDKRB2/Bradykinin B2 Receptor Antibody - Brain Hippocampus Neurons
BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
BDKRB2/Bradykinin B2 Receptor Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with BDKRB2 / BK-2.
BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
BDKRB2/Bradykinin B2 Receptor Antibody - Heart, Myocardial infarct
BDKRB2/Bradykinin B2 Receptor Antibody - Artery, Tunica media
BDKRB2/Bradykinin B2 Receptor Antibody - Brain Hippocampus Neurons
BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
BDKRB2/Bradykinin B2 Receptor Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with BDKRB2 / BK-2.
BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
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PathPlus™ Polyclonal Rabbit anti‑Human BDKRB2/Bradykinin B2 Receptor Antibody (C‑Terminus, IHC) LS‑A797

PathPlus™ Polyclonal Rabbit anti‑Human BDKRB2/Bradykinin B2 Receptor Antibody (C‑Terminus, IHC) LS‑A797

Antibody:
BDKRB2/Bradykinin B2 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, ICC
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$440
LS-A797-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
BDKRB2/Bradykinin B2 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, ICC
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Bradykinin B2 Receptor (BDKRB2) elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. BDKRB2 associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human BDKRB2/Bradykinin B2 Receptor
Synonyms
BDKRB2 | BK-2 receptor | Bradykinin type-2 receptor | B2R | Bradykinin B2 receptor | BRB2 | BK-2R | BK-2Rs | BK2 | B2 bradykinin receptor | B2bkr | BK-2 | BKR2 | Bradykinin receptor B2
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from C-Terminus of human BDKRB2 / BK-2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (94%); Mouse, Pig (83%).
Epitope
C-Terminus
Specificity
Human BDKRB2 / BK-2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BAHD1 (44%).
Applications
  • IHC
  • IHC - Paraffin (5 - 10 µg/ml)
  • ICC
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About BDKRB2/Bradykinin B2 Receptor
P30411 NM_000623 NP_000614.1

Validation

BDKRB2/Bradykinin B2 Receptor Antibody - Heart, Myocardial infarct
Heart, Myocardial infarct
Heart, Myocardial infarct

BDKRB2/Bradykinin B2 Receptor Antibody - Artery, Tunica media
Artery, Tunica media
Artery, Tunica media

BDKRB2/Bradykinin B2 Receptor Antibody - Brain Hippocampus Neurons
Brain Hippocampus Neurons
Brain Hippocampus Neurons

BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

BDKRB2/Bradykinin B2 Receptor Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with BDKRB2 / BK-2.
Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with BDKRB2 / BK-2.
Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with BDKRB2 / BK-2.

BDKRB2/Bradykinin B2 Receptor Antibody - Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.

LSBio Ratings

PathPlus™ BDKRB2/Bradykinin B2 Receptor Antibody (C-Terminus) for IHC, ICC LS-A797 has an LSBio Rating of
Publications (4.3)
Laboratory Validation Score (5)

Publications (4)

Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation. Savard M, Barbaz D, Blanger S, Mller-Esterl W, Bkaily G, D'orlans-Juste P, Cot J, Bovenzi V, Gobeil F. Journal of cellular physiology. 2008 216:234-44. (Mouse, Human, Rat)

Immunohistochemical localization of the bradykinin B1 and B2 receptors in human nasal mucosa. Shirasaki H, Kanaizumi E, Himi T. Mediators of inflammation. 2009 2009:102406. (IHC-P; Human)

Structure-activity relationships of novel peptide agonists of the human bradykinin B2 receptor. B[Character e9]langer S, Bovenzi V, C[Character f4]t[Character e9] J, Neugebauer W, Amblard M, Martinez J, Lammek B, Savard M, Gobeil F. Peptides. 2009 Apr;30:777-87.

Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer. Dubuc C, Savard M, Bovenzi V, Lessard A, Fortier A, Côté J, Neugebauer W, Rizzolio F, Geha S, Giordano A, Chemtob S, Gobeil F. Oncotarget. 2018 January;9:9885-9906. (Human)

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Date Requested: 9/24/2021