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Catalog Number Size Price
LS-A799-50 50 µg (1 mg/ml) $440 
B1R / BDKRB1 Antibody - Brain Hippocampus Neurons
B1R / BDKRB1 Antibody - Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
B1R / BDKRB1 Antibody - Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
B1R / BDKRB1 Antibody - Brain Hippocampus Neurons
B1R / BDKRB1 Antibody - Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
B1R / BDKRB1 Antibody - Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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PathPlus™ Polyclonal Rabbit anti‑Human B1R / BDKRB1 Antibody (Cytoplasmic Domain, IHC) LS‑A799

PathPlus™ Polyclonal Rabbit anti‑Human B1R / BDKRB1 Antibody (Cytoplasmic Domain, IHC) LS‑A799

Antibody:
B1R / BDKRB1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$440
LS-A799-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
B1R / BDKRB1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Bradykinin receptor (BDKRB1) is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human B1R / BDKRB1
Synonyms
BDKRB1 | BKB1R | Bradykinin receptor 1 | B1BKR | B1R | Bk b1 receptor | BK-1 receptor | BRADYB1 | Bradykinin receptor B1 | Kinin b1 receptor | B1 bradykinin receptor | BKR1 | Bradykinin B1 receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human BDKRB1. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (94%); Horse (81%).
Epitope
Cytoplasmic Domain
Specificity
Human BDKRB1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC - Paraffin (10 - 20 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • ELISA
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About B1R / BDKRB1
P46663 NM_000710 NP_000701.2

Validation

B1R / BDKRB1 Antibody - Brain Hippocampus Neurons
Brain Hippocampus Neurons
Brain Hippocampus Neurons

B1R / BDKRB1 Antibody - Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.

B1R / BDKRB1 Antibody - Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.

LSBio Ratings

PathPlus™ B1R / BDKRB1 Antibody (Cytoplasmic Domain) for IHC LS-A799 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (5)

Publications (2)

Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin B1 receptor agonist in a glioma rat model. Ct J, Bovenzi V, Savard M, Dubuc C, Fortier A, Neugebauer W, Tremblay L, Mller-Esterl W, Tsanaclis AM, Lepage M, Fortin D, Gobeil F. PloS one. 2012 7:e37485. (WB; Human)

Structure-activity relationships of novel peptide agonists of the human bradykinin B2 receptor. B[Character e9]langer S, Bovenzi V, C[Character f4]t[Character e9] J, Neugebauer W, Amblard M, Martinez J, Lammek B, Savard M, Gobeil F. Peptides. 2009 Apr;30:777-87.

Customer Reviews (0)


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Requested From: United States
Date Requested: 9/24/2021