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Catalog Number Size Price
LS-A1213-50 50 µg (1 mg/ml) $460 
ADGRG1 / GPR56 Antibody - Brain, Glioblastoma
ADGRG1 / GPR56 Antibody - Lung, adenocarcinoma
ADGRG1 / GPR56 Antibody - Breast, Carcinoma
ADGRG1 / GPR56 Antibody - Human, Brain, neurons and glia: Formalin-Fixed Paraffin-Embedded (FFPE)
ADGRG1 / GPR56 Antibody - Brain, Glioblastoma
ADGRG1 / GPR56 Antibody - Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ADGRG1 / GPR56 Antibody - Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ADGRG1 / GPR56 Antibody - Brain, Glioblastoma
ADGRG1 / GPR56 Antibody - Lung, adenocarcinoma
ADGRG1 / GPR56 Antibody - Breast, Carcinoma
ADGRG1 / GPR56 Antibody - Human, Brain, neurons and glia: Formalin-Fixed Paraffin-Embedded (FFPE)
ADGRG1 / GPR56 Antibody - Brain, Glioblastoma
ADGRG1 / GPR56 Antibody - Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ADGRG1 / GPR56 Antibody - Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human ADGRG1 / GPR56 Antibody (Cytoplasmic Domain, IHC) LS‑A1213

PathPlus™ Polyclonal Rabbit anti‑Human ADGRG1 / GPR56 Antibody (Cytoplasmic Domain, IHC) LS‑A1213

Antibody:
ADGRG1 / GPR56 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-A1213-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ADGRG1 / GPR56 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Isoforms show differences in receptor signaling, specifically in serum response element (SRE) transcriptional activation upon overexpression. Overexpression inhibits melanoma tumor growth and metastasis and, during melanoma progression, regulates VEGFA production and angiogenesis through PRKCA; unprocessed GPR56 is inhibiting and GPR56 NT is activating angiogenesis. Required for normal cortical development and regulation of neuroprogenitor cells proliferation. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human ADGRG1 / GPR56
Synonyms
ADGRG1 | BFPP | G-protein coupled receptor 56 | GPR56 | G protein-coupled receptor 56 | TM7LN4 | Protein TM7XN1 | TM7XN1
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Predicted
Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from 1st cytoplasmic domain of human GPR56. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%); Pig (95%); Bovine, Rabbit (89%).
Epitope
Cytoplasmic Domain
Specificity
Human GPR56. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (2.5 - 5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • ICC
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ADGRG1 / GPR56
Q9Y653 NM_005682 NP_005673.3

Validation

ADGRG1 / GPR56 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

ADGRG1 / GPR56 Antibody - Lung, adenocarcinoma
Lung, adenocarcinoma
Lung, adenocarcinoma

ADGRG1 / GPR56 Antibody - Breast, Carcinoma
Breast, Carcinoma
Breast, Carcinoma

ADGRG1 / GPR56 Antibody - Human, Brain, neurons and glia: Formalin-Fixed Paraffin-Embedded (FFPE)
Human, Brain, neurons and glia: Formalin-Fixed Paraffin-Embedded (FFPE)
Human, Brain, neurons and glia: Formalin-Fixed Paraffin-Embedded (FFPE)

ADGRG1 / GPR56 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

ADGRG1 / GPR56 Antibody - Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ADGRG1 / GPR56 Antibody - Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR56 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ ADGRG1 / GPR56 Antibody (Cytoplasmic Domain) for IHC LS-A1213 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/13/2022