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Catalog Number Size Price
LS-B6587-50 50 µl (1 mg/ml) $460 
ACVRL1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Immunofluorescence analysis of HeLa cells, using ACVL1 Antibody. The picture on the right is blocked with the synthesized peptide.
ACVRL1 Antibody - Western blot analysis of lysates from K562 cells, using ACVL1 Antibody. The lane on the right is blocked with the synthesized peptide.
ACVRL1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACVRL1 Antibody - Immunofluorescence analysis of HeLa cells, using ACVL1 Antibody. The picture on the right is blocked with the synthesized peptide.
ACVRL1 Antibody - Western blot analysis of lysates from K562 cells, using ACVL1 Antibody. The lane on the right is blocked with the synthesized peptide.
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PathPlus™ Polyclonal Rabbit anti‑Human ACVRL1 Antibody (aa196‑245, IHC, IF, WB) LS‑B6587

PathPlus™ Polyclonal Rabbit anti‑Human ACVRL1 Antibody (aa196‑245, IHC, IF, WB) LS‑B6587

Note: This antibody replaces LS-C118880
Antibody:
ACVRL1 Rabbit anti-Human Polyclonal (aa196-245) Antibody
Application:
IHC-P, IF, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B6587-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ACVRL1 Rabbit anti-Human Polyclonal (aa196-245) Antibody
Application:
IHC-P, IF, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
ACVRL1 (Activin A receptor, type II-like 1, activin receptor-like kinase 1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1 is most highly expressed in human placenta and lung. ACVRL1 protein deficiency and mutations in the gene cause hemorrhagic telangiectasia type 2 (HHT2), also known as Rendu-Osler-Weber syndrome 2 (ORW2), and also lead to pulmonary arteriovenous malformations. ACVRL1 interaction with low-density lipoprotein (LDL) also implicates it in the early phases of atherosclerosis. In immunohistochemistry of normal tissue, ACVRL1 has cytoplasmic positivity in the lung, placenta, brain, endocrine tissues, gastrointestinal tissue, gallbladder, pancreas, kidney, testis, smooth muscle, skin, and immune tissues. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 600376: 08/22/2019: URL: https://omim.org/; Nature Communications. 7: 13516, PMID: 27869117;
Target
Human ACVRL1
Synonyms
ACVRL1 | ALK1 | Activin receptor-like kinase 1 | ALK-1 | ACVRLK1 | HHT | HHT2 | SKR3 | TSR-I | ORW2
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human ACVL1. (AA Range: 196-245)
Epitope
aa196-245
Specificity
ACVL1 Antibody detects endogenous levels of total ACVL1 protein.
Applications
  • IHC - Paraffin (10 µg/ml)
  • Immunofluorescence (1:100 - 1:500)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:20000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western Blot: Predicted MW 56 kDa
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ACVRL1
P37023 NM_000020 NP_000011.2

Validation

ACVRL1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

ACVRL1 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)

ACVRL1 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

ACVRL1 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

ACVRL1 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ ACVRL1 Antibody (aa196-245) for IHC, IF/Immunofluorescence, WB/Western LS-B6587 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/19/2024