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Catalog Number Size Price
LS-B16122-50 50 µl (1 mg/ml) $460 
Actin Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Actin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Actin Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Actin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PathPlus™ Monoclonal Mouse anti‑Human Actin Antibody (clone ABT‑ACTN, IHC, WB) LS‑B16122

PathPlus™ Monoclonal Mouse anti‑Human Actin Antibody (clone ABT‑ACTN, IHC, WB) LS‑B16122

Note: This antibody replaces LS-C744447
Antibody:
Actin Mouse anti-Human Monoclonal (ABT-ACTN) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B16122-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Actin Mouse anti-Human Monoclonal (ABT-ACTN) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Actins are ubiquitously expressed proteins that are a major component of the cytoskeleton. Actin is expressed in heart and skeletal striated muscle tissue, and in certain smooth muscle tissues. It regulates motility and controls cells structure in both muscle and non-muscle cells (where it is present in the cytoplasm as well). Pan-actin antibodies can be used to identify actin expression and localization in normal and disease states. Pan-actin antibodies can be used to label myotubes, myoblasts and fibroblasts. They are useful for determining total actin levels to compare against the differential expression of specific actins in normal versus diseased tissue, such as kidney tissue in diabetes. References: Cytoskeleton (Hoboken). 2010 Nov;67(11):729-43, PMID: 20862689; Clin Proteom 8, 15 (2011) doi:10.1186/1559-0275-8-15; Molecular & Cellular Proteomics. 2012. 11 (8): 255-271, DOI: 10.1074/mcp.M111.015099
Target
Human Actin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Monoclonal
Clone
ABT-ACTN
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Synthetic Actin-pan
Applications
  • IHC (1:200 - 1:400)
  • IHC - Paraffin (1:50)
  • Western blot (1:200 - 1:400)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Use Heat-induced epitope retrieval (HIER) Citrate buffer of pH 6.0 Recommended IHC controls tissues are Normal Colon, Cardiac muscle, Skeletal muscle. Resulting localization is Cytoplasmic
Presentation
0.5% BSA,  0.1% Kathon, Tris-Buffered Saline, DI H2O and 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

Validation

Actin Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

Actin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ Actin Antibody (clone ABT-ACTN) for IHC, WB/Western LS-B16122 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/25/2022