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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-B7709-50 50 µl $425 
TPH1 / Tryptophan Hydroxylase Antibody - Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
TPH1 / Tryptophan Hydroxylase Antibody - Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.
TPH1 / Tryptophan Hydroxylase Antibody - Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
TPH1 / Tryptophan Hydroxylase Antibody - Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.
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PathPlus™ Polyclonal TPH1 / Tryptophan Hydroxylase Antibody (IHC, WB) LS‑B7709

PathPlus™ Polyclonal TPH1 / Tryptophan Hydroxylase Antibody (IHC, WB) LS‑B7709

Note: This antibody replaces LS-C225
Antibody:
Sheep Polyclonal to Rabbit TPH1 / Tryptophan Hydroxylase
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Rabbit, Human, Rat, Mammal
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425 
LS-B7709-50
50 µl
Toll Free North America
866-819-4732

Overview

Antibody:
Sheep Polyclonal to Rabbit TPH1 / Tryptophan Hydroxylase
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Rabbit, Human, Rat, Mammal
Format:
Unconjugated, Unmodified

Specifications

Description
TPH1 / TPH (tryptophan hydroxylase 1) is a member of the aromatic amino acid hydroxylase family that catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others. References: NeuroReport: August 5th, 2009 - Volume 20 - Issue 12 - p 1125-1128
Target
Rabbit TPH1 / Tryptophan Hydroxylase
Synonyms
TPH1 | L-tryptophan hydroxylase | TRPH | Tryptophan 5-hydroxylase 1 | Tryptophan 5-monooxygenase 1 | TPRH | Tryptophan hydroxylase 1 | TPH
Host
Sheep
Reactivity
Rabbit, Human, Rat, Mammal (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • IHC - Frozen (1:1000)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant rabbit tryptophan hydroxylase, isolated as inclusion bodies from E. coli and purified by preparative SDS-PAGE.
Specificity
Specific for the ~55k tryptophan hydroxylase protein
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 50% Glycerol, 100 ug/ml BSA
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TPH1 / Tryptophan Hydroxylase
P17752 NM_004179 NP_004170.1

Validation

TPH1 / Tryptophan Hydroxylase Antibody - Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

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Requested From: United States
Date Requested: 2/21/2020