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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-B7046-50 50 µl (1 mg/ml) $425 
SST / Somatostatin Antibody - Anti-SST / Somatostatin antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
SST / Somatostatin Antibody - Western blot analysis of lysates from A549 cells, using Somatostatin Antibody. The lane on the right is blocked with the synthesized peptide.
SST / Somatostatin Antibody - Anti-SST / Somatostatin antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
SST / Somatostatin Antibody - Western blot analysis of lysates from A549 cells, using Somatostatin Antibody. The lane on the right is blocked with the synthesized peptide.
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PathPlus™ Polyclonal SST / Somatostatin Antibody (aa10‑59, IHC, WB) LS‑B7046

PathPlus™ Polyclonal SST / Somatostatin Antibody (aa10‑59, IHC, WB) LS‑B7046

Note: This antibody replaces LS-C118579
Antibody:
Rabbit Polyclonal to Human SST / Somatostatin
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425 
LS-B7046-50
50 µl
1 mg/ml
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human SST / Somatostatin
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
SST (growth hormone-inhibiting hormone, somatostatin, SMST) is an inhibitory cyclic peptide produced by somatostatinergic neurons in the brain and delta cells in pancreatic islets, the duodenum and the pyloric antrum of the stomach. SST functions to regulate the endocrine system, neurotransmission and cell proliferation by inhibiting neurotransmitter and hormone release upon binding to various SST receptors. Deregulated SST is associated with excitation/inhibition balance in various neurodegenerative and neuropsychiatric disorders. Cognitive deficits in Alzheimer’s disease correlate with a decrease in SST expression in the brain. A decrease in SST expression has also been reported in Parkinson’s disease, major depressive disorder and schizophrenia. Somatostatin release also correlates with seizures, and it is highly expressed in regions of the brain related to seizures. Finally, pretreatment with SST may help prevent dopaminergic neuronal degeneration in Parkinson’s disease. In immunohistochemistry of normal tissue, SST has secretory and extracellular positivity in the hypothalamus, adrenal medulla and cortex in the brain, in islets of Langerhans in the pancreas, and in gastrointestinal neuroendocrine cells. References: PLoS One. 2019 May 28;14(5):e0217392, PMID: 31136617; Mol Med Rep. 2015 Jul;12(1):1002-8, PMID: 25777539; Front Endocrinol (Lausanne). 2012 Dec 6;3:154, PMID: 23230430;
Target
Human SST / Somatostatin
Synonyms
SST | Somatostatin-28 | SMST | Somatostatin-14 | Somatostatin
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide from human Somatostatin. (AA Range: 8-59)
Epitope
aa10-59
Specificity
Somatostatin Antibody detects endogenous levels of total Somatostatin protein.
Usage
Western Blot: Predicted MW 12 kDa
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SST / Somatostatin
P61278 NM_001048 NP_001039.1

Validation

SST / Somatostatin Antibody - Anti-SST / Somatostatin antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-SST / Somatostatin antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-SST / Somatostatin antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

LSBio Ratings

PathPlus™ SST / Somatostatin Antibody (aa10-59) for IHC, WB/Western LS-B7046 has an LSBio Rating of
Laboratory Validation Score (5)

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Requested From: United States
Date Requested: 4/5/2020