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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-B7715-50 50 µl $425 
SLC6A3 / Dopamine Transporter Antibody - Anti-SLC6A3 / Dopamine Transporter antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
SLC6A3 / Dopamine Transporter Antibody - Western blot of human caudate lysate showing specific immunolabeling of the ~88k DAT protein.
SLC6A3 / Dopamine Transporter Antibody - Anti-SLC6A3 / Dopamine Transporter antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
SLC6A3 / Dopamine Transporter Antibody - Western blot of human caudate lysate showing specific immunolabeling of the ~88k DAT protein.
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PathPlus™ Polyclonal SLC6A3 / Dopamine Transporter Antibody (EL2 Region, IHC, WB) LS‑B7715

PathPlus™ Polyclonal SLC6A3 / Dopamine Transporter Antibody (EL2 Region, IHC, WB) LS‑B7715

Note: This antibody replaces LS-C219
Antibody:
Rabbit Polyclonal to Human SLC6A3 / Dopamine Transporter
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425 
LS-B7715-50
50 µl
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human SLC6A3 / Dopamine Transporter
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
SLC6A3 / Dopamine Transporter is a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human SLC6A3 / Dopamine Transporter
Synonyms
SLC6A3 | DA transporter | DAT1 | DAT
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • IHC - Frozen (1:1000)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Peptide from the extracellular loop 2 (EL2) region of human dopamine transporter (DAT), conjugated to keyhole limpet hemocyanin (KLH).
Epitope
EL2 Region
Specificity
Specific for the ~88k DAT protein in Western blots
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 50% Glycerol, 100 ug/ml BSA
Storage
Short term: store at -20°C. Long term: store at -80°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SLC6A3 / Dopamine Transporter
Q01959 NM_001044 NP_001035.1

Validation

SLC6A3 / Dopamine Transporter Antibody - Anti-SLC6A3 / Dopamine Transporter antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-SLC6A3 / Dopamine Transporter antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-SLC6A3 / Dopamine Transporter antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

LSBio Ratings

PathPlus™ SLC6A3 / Dopamine Transporter Antibody (EL2 Region) for IHC, WB/Western LS-B7715 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma. Schrödter S, Braun M, Syring I, Klümper N, Deng M, Schmidt D, Perner S, Müller SC, Ellinger J. Molecular cancer. 2016 15:10. (WB; Human)

Customer Reviews (0)


Requested From: United States
Date Requested: 4/8/2020