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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-A412-50 50 µg (1 mg/ml) $425 
RAIG2 / GPRC5B Antibody - Hodgkin's lymphoma
RAIG2 / GPRC5B Antibody - Non-Hodgkin's lymphoma
RAIG2 / GPRC5B Antibody - Anti-GPRC5B antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
RAIG2 / GPRC5B Antibody - Skin, Malignant Melanoma
RAIG2 / GPRC5B Antibody - Hodgkin's lymphoma
RAIG2 / GPRC5B Antibody - Non-Hodgkin's lymphoma
RAIG2 / GPRC5B Antibody - Anti-GPRC5B antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
RAIG2 / GPRC5B Antibody - Skin, Malignant Melanoma
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PathPlus™ Polyclonal Rabbit anti‑Human RAIG2 / GPRC5B Antibody (C‑Terminus, IHC) LS‑A412

PathPlus™ Polyclonal Rabbit anti‑Human RAIG2 / GPRC5B Antibody (C‑Terminus, IHC) LS‑A412

Antibody:
Rabbit Polyclonal to Human RAIG2 / GPRC5B
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A412-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human RAIG2 / GPRC5B
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
GPRC5B is a G protein-coupled receptor induced by retinoids. GPRC5B shows some homology to the metabotropic glutamate receptor-like family of GPCRs. In mice, GPRC5B has been shown to regulate neuronal differentiation in the developing neocortex. Additionally, GPRC5B is expressed in breast cancer cell lines versus absence in normal control cells, and may be an effective biomarker for breast cancer. In immunohistochemistry, GPRC5B has membranous and cytoplasmic positivity throughout the central nervous system, the kidney, reproductive tissues, the breast, gastrointestinal tract, kidney and a few other tissues. References: Front Pharmacol. 2018 May 22;9:431, PMID: 29872392; Development 2013 140: 4335-4346; doi: 10.1242/dev.099754
Target
Human RAIG2 / GPRC5B
Synonyms
GPRC5B | A-69G12.1 | RAIG2 | RAIG-2
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Predicted
Bovine, Dog, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2 - 5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 20 amino acid peptide from C-Terminus of human GPRC5B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Orangutan (95%); Panda, Dog, Bovine, Horse, Turkey (90%); Pig, Opossum (85%).
Epitope
C-Terminus
Specificity
Human GPRC5B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About RAIG2 / GPRC5B
Q9NZH0 NM_016235 NP_057319.1

Validation

RAIG2 / GPRC5B Antibody - Hodgkin's lymphoma
Hodgkin's lymphoma
Hodgkin's lymphoma

RAIG2 / GPRC5B Antibody - Non-Hodgkin's lymphoma
Non-Hodgkin's lymphoma
Non-Hodgkin's lymphoma

RAIG2 / GPRC5B Antibody - Anti-GPRC5B antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPRC5B antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPRC5B antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

RAIG2 / GPRC5B Antibody - Skin, Malignant Melanoma
Skin, Malignant Melanoma
Skin, Malignant Melanoma

LSBio Ratings

PathPlus™ RAIG2 / GPRC5B Antibody (C-Terminus) for IHC LS-A412 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Requested From: United States
Date Requested: 6/5/2020