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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-A7962-50 50 µg (1 mg/ml) $425 
PAK6 Antibody - Colon, Carcinoma
PAK6 Antibody - Lung, Non Small-Cell Carcinoma
PAK6 Antibody - Breast, carcinoma
PAK6 Antibody - Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PAK6 Antibody - Brain, Glioblastoma
PAK6 Antibody - Colon, Carcinoma
PAK6 Antibody - Lung, Non Small-Cell Carcinoma
PAK6 Antibody - Breast, carcinoma
PAK6 Antibody - Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PAK6 Antibody - Brain, Glioblastoma
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PathPlus™ PAK6 Antibody Linker Domain Polyclonal IHC LS‑A7962

PathPlus™ PAK6 Antibody Linker Domain Polyclonal IHC LS‑A7962

Antibody:
Rabbit Polyclonal to Human PAK6
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A7962-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human PAK6
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
PAK6 is a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human PAK6
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (4.8 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 19 amino acid peptide from Linker domain of human PAK6. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Monkey, Panda, Bovine (95%); Marmoset, Rat, Elephant, Bat, Dog, Rabbit, Horse (89%); Mouse (84%).
Blocking Peptide
LS-E29294 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A7962. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Linker Domain
Specificity
Human PAK6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except AGBL5 (42%).
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PAK6
Q9NQU5 NM_020168 NP_064553.1

Validation

PAK6 Antibody - Colon, Carcinoma
Colon, Carcinoma
Colon, Carcinoma

PAK6 Antibody - Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma

PAK6 Antibody - Breast, carcinoma
Breast, carcinoma
Breast, carcinoma

PAK6 Antibody - Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PAK6 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

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Requested From: United States
Date Requested: 11/22/2019