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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-A1921-50 50 µg (1 mg/ml) $425 
P2RY8 / P2Y8 Antibody - Brain, cortex, neurons
P2RY8 / P2Y8 Antibody - Brain, Glioblastoma
P2RY8 / P2Y8 Antibody - Brain, Amygdala, neurons and glia
P2RY8 / P2Y8 Antibody - Anti-P2RY8 / P2Y8 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
P2RY8 / P2Y8 Antibody - Anti-P2RY8 / P2Y8 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
P2RY8 / P2Y8 Antibody - Brain, cortex, neurons
P2RY8 / P2Y8 Antibody - Brain, Glioblastoma
P2RY8 / P2Y8 Antibody - Brain, Amygdala, neurons and glia
P2RY8 / P2Y8 Antibody - Anti-P2RY8 / P2Y8 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
P2RY8 / P2Y8 Antibody - Anti-P2RY8 / P2Y8 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ P2RY8 / P2Y8 Antibody Cytoplasmic Domain Polyclonal IHC LS‑A1921

PathPlus™ P2RY8 / P2Y8 Antibody Cytoplasmic Domain Polyclonal IHC LS‑A1921

Note: This antibody replaces LS-C91216
Antibody:
Rabbit Polyclonal to Human P2RY8 / P2Y8
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A1921-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human P2RY8 / P2Y8
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
P2RY8 is an Orphan-A GPCR with an unknown ligand. This protein shares low similarity to the Xenopus P2Y8 receptor (CAA68213.1, 30% protein similarity). It has been shown to contribute to the promote B-cell clustering within germinal centers, and mutations in P2RY8 have been found in germinal center derived lymphomas. Haematologica. 2018 Aug; 103(8): 1252–1255.
Target
Human P2RY8 / P2Y8
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2 - 4 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 17 amino acid peptide from 1st cytoplasmic domain of human P2RY8 / P2Y8. Percent identity with other species by BLAST analysis: Human (100%); Marmoset (94%); Gorilla, Elephant (88%); Panda (82%).
Blocking Peptide
LS-E28435 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A1921. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Cytoplasmic Domain
Specificity
Human P2RY8 / P2Y8. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR174 (41%).
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About P2RY8 / P2Y8
Q86VZ1 NM_178129 NP_835230.1

Validation

P2RY8 / P2Y8 Antibody - Brain, cortex, neurons
Brain, cortex, neurons
Brain, cortex, neurons

P2RY8 / P2Y8 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

P2RY8 / P2Y8 Antibody - Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia

P2RY8 / P2Y8 Antibody - Anti-P2RY8 / P2Y8 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY8 / P2Y8 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY8 / P2Y8 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

P2RY8 / P2Y8 Antibody - Anti-P2RY8 / P2Y8 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY8 / P2Y8 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY8 / P2Y8 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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Requested From: United States
Date Requested: 11/21/2019