Products
Services
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-A171-50 50 µg (1 mg/ml) $425 
NPBWR1 / GPR7 Antibody - Brain, Globus Pallidus
NPBWR1 / GPR7 Antibody - Brain, hippocampus CA4
NPBWR1 / GPR7 Antibody - Anti-NPBWR1 / GPR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
NPBWR1 / GPR7 Antibody - Anti-NPBWR1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
NPBWR1 / GPR7 Antibody - Anti-NPBWR1 / GPR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
NPBWR1 / GPR7 Antibody - Brain, Globus Pallidus
NPBWR1 / GPR7 Antibody - Brain, hippocampus CA4
NPBWR1 / GPR7 Antibody - Anti-NPBWR1 / GPR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
NPBWR1 / GPR7 Antibody - Anti-NPBWR1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
NPBWR1 / GPR7 Antibody - Anti-NPBWR1 / GPR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
1 of 5
2 of 5
3 of 5
4 of 5
5 of 5

PathPlus™ Polyclonal Rabbit anti‑Human NPBWR1 / GPR7 Antibody (Cytoplasmic Domain, IHC) LS‑A171

PathPlus™ Polyclonal Rabbit anti‑Human NPBWR1 / GPR7 Antibody (Cytoplasmic Domain, IHC) LS‑A171

Antibody:
Rabbit Polyclonal to Human NPBWR1 / GPR7
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A171-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human NPBWR1 / GPR7
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Neuropeptides B/W receptor 1 (NPBWR1, GPR7) interacts specifically with a number of opioid ligands. It is a receptor for neuropeptides B and W, which regulate fear and stress. It is upregulated in Schwann cells associated with neuropathic pain and is thought to inhibit inflammatory pain responses. It is further involved in neuroendocrine system regulation, food intake and the organization of other signals. NPBWR1 as a higher affinity for neuropeptide B. In immunohistochemistry, NPBWR1 has strong membranous positivity in the amygdala and stria terminalis in the brain, with some expression in the pituitary, liver, urinary bladder, skin, and on granulocytes. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human NPBWR1 / GPR7
Synonyms
NPBWR1 | G protein-coupled receptor 7 | GPR7 | Neuropeptide B/W receptor 1 | Neuropeptides B/W receptor 1 | G-protein coupled receptor 7
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Predicted
Bovine, Horse, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (11 - 22 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 17 amino acid peptide from 2nd cytoplasmic domain of human NPBWR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Panda (100%); Bovine, Horse, Rabbit (94%); Marmoset, Mouse, Rat (88%); Elephant (82%).
Blocking Peptide
LS-E28383 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A171. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Cytoplasmic Domain
Specificity
Human NPBWR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About NPBWR1 / GPR7
P48145 NM_005285 NP_005276.2

Validation

NPBWR1 / GPR7 Antibody - Brain, Globus Pallidus
Brain, Globus Pallidus
Brain, Globus Pallidus

NPBWR1 / GPR7 Antibody - Brain, hippocampus CA4
Brain, hippocampus CA4
Brain, hippocampus CA4

NPBWR1 / GPR7 Antibody - Anti-NPBWR1 / GPR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR1 / GPR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR1 / GPR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NPBWR1 / GPR7 Antibody - Anti-NPBWR1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NPBWR1 / GPR7 Antibody - Anti-NPBWR1 / GPR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR1 / GPR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR1 / GPR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ NPBWR1 / GPR7 Antibody (Cytoplasmic Domain) for IHC LS-A171 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Requested From: United States
Date Requested: 7/5/2020