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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A2331-50 50 µg (1 mg/ml) $425 
Nor-1 / NR4A3 Antibody - Lung, Non Small-Cell Carcinoma
Nor-1 / NR4A3 Antibody - Ovary, Carcinoma
Nor-1 / NR4A3 Antibody - Prostate, Carcinoma
Nor-1 / NR4A3 Antibody - Anti-NR4A3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Nor-1 / NR4A3 Antibody - Anti-Nor-1 / NR4A3 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Nor-1 / NR4A3 Antibody - Anti-Nor-1 / NR4A3 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Nor-1 / NR4A3 Antibody - Anti-NR4A3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Nor-1 / NR4A3 Antibody - Lung, Non Small-Cell Carcinoma
Nor-1 / NR4A3 Antibody - Ovary, Carcinoma
Nor-1 / NR4A3 Antibody - Prostate, Carcinoma
Nor-1 / NR4A3 Antibody - Anti-NR4A3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Nor-1 / NR4A3 Antibody - Anti-Nor-1 / NR4A3 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Nor-1 / NR4A3 Antibody - Anti-Nor-1 / NR4A3 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Nor-1 / NR4A3 Antibody - Anti-NR4A3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human Nor‑1 / NR4A3 Antibody (Internal, IHC) LS‑A2331

PathPlus™ Polyclonal Rabbit anti‑Human Nor‑1 / NR4A3 Antibody (Internal, IHC) LS‑A2331

Antibody:
Rabbit Polyclonal to Human Nor-1 / NR4A3
Application:
IHC, IHC-P
Reactivity:
Human, Bovine, Dog, Pig, Rabbit
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A2331-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human Nor-1 / NR4A3
Application:
IHC, IHC-P
Reactivity:
Human, Bovine, Dog, Pig, Rabbit
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Nor-1 / NR4A3 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human Nor-1 / NR4A3
Synonyms
NR4A3 | CHN | MINOR | NOR1 | Neuron-derived orphan receptor | Nuclear hormone receptor NOR-1 | Nor-1 | CSMF | Orphan receptor nor1 | TEC receptor
Host
Rabbit
Reactivity
Human, Bovine, Dog, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Rat, Bat, Hamster, Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 17 amino acid peptide from internal region of human NR4A3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Bovine, Dog, Elephant, Panda, Rabbit, Pig, Platypus (100%); Marmoset, Mouse, Rat, Bat, Hamster, Opossum, Turkey, Chicken (94%).
Blocking Peptide
LS-E28548 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A2331. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Internal
Specificity
Human NR4A3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Usage
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 10 ug/ml.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About Nor-1 / NR4A3
Q92570 NM_006981 NP_008912.2

Validation

Nor-1 / NR4A3 Antibody - Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma

Nor-1 / NR4A3 Antibody - Ovary, Carcinoma
Ovary, Carcinoma
Ovary, Carcinoma

Nor-1 / NR4A3 Antibody - Prostate, Carcinoma
Prostate, Carcinoma
Prostate, Carcinoma

Nor-1 / NR4A3 Antibody - Anti-NR4A3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR4A3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR4A3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Nor-1 / NR4A3 Antibody - Anti-Nor-1 / NR4A3 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Nor-1 / NR4A3 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Nor-1 / NR4A3 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Nor-1 / NR4A3 Antibody - Anti-Nor-1 / NR4A3 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Nor-1 / NR4A3 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Nor-1 / NR4A3 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Nor-1 / NR4A3 Antibody - Anti-NR4A3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR4A3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR4A3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ Nor-1 / NR4A3 Antibody (Internal) for IHC LS-A2331 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Requested From: United States
Date Requested: 5/29/2020