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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A1533-50 50 µg (1 mg/ml) $425 
MCHR1 Antibody - Lung, small cell carcinoma
MCHR1 Antibody - Brain, Pituitary
MCHR1 Antibody - Brain, Hypothalamus
MCHR1 Antibody - Anti-MCHR1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MCHR1 Antibody - Anti-MCHR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MCHR1 Antibody - Anti-MCHR1 antibody IHC of human Soft Tissue, Liposarcoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MCHR1 Antibody - Lung, small cell carcinoma
MCHR1 Antibody - Brain, Pituitary
MCHR1 Antibody - Brain, Hypothalamus
MCHR1 Antibody - Anti-MCHR1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MCHR1 Antibody - Anti-MCHR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MCHR1 Antibody - Anti-MCHR1 antibody IHC of human Soft Tissue, Liposarcoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal MCHR1 Antibody (N‑Terminus, IHC) LS‑A1533

PathPlus™ Polyclonal MCHR1 Antibody (N‑Terminus, IHC) LS‑A1533

Antibody:
Rabbit Polyclonal to Human MCHR1
Application:
IHC, IHC-P
Reactivity:
Human, Pig
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A1533-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human MCHR1
Application:
IHC, IHC-P
Reactivity:
Human, Pig
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Melanin-concentrating hormone receptor 1 (MCHR1) is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR1 does not seem to bind somatostatin. In immunohistochemsitry, MCHR1 has highest membranous positivity in the cerebral cortex and hypothalamus and is found throughout the nervous system, with low levels of expression in the liver, heart and a few other tissues throughout the body. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human MCHR1
Synonyms
MCHR1 | G-protein coupled receptor 24 | G protein-coupled receptor 24 | GPR24 | MCH-1R | MCH receptor 1 | MCH-R1 | MCH1R | Somatostatin-like receptor 1 | MCH 1 receptor | MCHR | SLC-1 | MCHR-1 | SLC1
Host
Rabbit
Reactivity
Human, Pig (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (3 - 5 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 20 amino acid peptide from N-Terminus extracellular domain of human MCHR1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Panda, Pig (100%); Monkey (95%); Bovine, Horse (90%); Dog (85%); Mouse, Hamster, Rabbit (80%).
Epitope
N-Terminus
Specificity
Human MCHR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MCHR1
Q99705 NM_005297 NP_005288.3

Validation

MCHR1 Antibody - Lung, small cell carcinoma
Lung, small cell carcinoma
Lung, small cell carcinoma

MCHR1 Antibody - Brain, Pituitary
Brain, Pituitary
Brain, Pituitary

MCHR1 Antibody - Brain, Hypothalamus
Brain, Hypothalamus
Brain, Hypothalamus

MCHR1 Antibody - Anti-MCHR1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MCHR1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MCHR1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MCHR1 Antibody - Anti-MCHR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MCHR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MCHR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MCHR1 Antibody - Anti-MCHR1 antibody IHC of human Soft Tissue, Liposarcoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MCHR1 antibody IHC of human Soft Tissue, Liposarcoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MCHR1 antibody IHC of human Soft Tissue, Liposarcoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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Requested From: United States
Date Requested: 2/18/2020