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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-A111-50 50 µg (1 mg/ml) $425 
GPR22 Antibody - Anti-GPR22 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPR22 Antibody - Brain, Hypothalamus
GPR22 Antibody - Anti-GPR22 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPR22 Antibody - Brain, Hypothalamus
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PathPlus™ GPR22 Antibody Cytoplasmic Domain Polyclonal IHC LS‑A111

PathPlus™ GPR22 Antibody Cytoplasmic Domain Polyclonal IHC LS‑A111

Antibody:
Rabbit Polyclonal to Human GPR22
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bat, Hamster, Horse, Chicken, Xenopus, Zebrafish
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A111-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human GPR22
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bat, Hamster, Horse, Chicken, Xenopus, Zebrafish
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
GPR22 is an orphan G protein-coupled receptor (GPCR). It is involved in ciliogenesis in zebrafish, and shows a highly restricted expression pattern in humans and rodents, with abundant and selective expression in the brain and heart. GPR22 protein expression has been detected in cardiac myocytes and coronary arteries by immunohistochemistry. It has been hypothesized to have a protective role for in response to hemodynamic stress resulting from increased afterload in the heart. PLOS One/doi.org/10.1371/journal.pone.0110484; 01 AUG 2008https://doi.org/10.1152/ajpheart.00368.2008
Target
Human GPR22
Host
Rabbit
Reactivity
Human, Monkey, Bat, Hamster, Horse, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bovine, Pig, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (4 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR22. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Bat, Hamster, Elephant, Panda, Horse, Turkey, Chicken, Platypus, Lizard, Xenopus, Pufferfish, Zebrafish, Stickleback (100%); Mouse, Rat, Rabbit, Pig (95%); Bovine (90%).
Blocking Peptide
LS-E28138 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A111. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Cytoplasmic Domain
Specificity
Human GPR22. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GPR22
Q99680 NM_005295 NP_005286.2

Validation

GPR22 Antibody - Anti-GPR22 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR22 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR22 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPR22 Antibody - Brain, Hypothalamus
Brain, Hypothalamus
Brain, Hypothalamus

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Requested From: United States
Date Requested: 12/16/2019