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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A4105-50 50 µg (1 mg/ml) $425 
GALR1 / Galanin Receptor 1 Antibody - Lung, non small cell carcinoma
GALR1 / Galanin Receptor 1 Antibody - Brain, Parkinson's soft body
GALR1 / Galanin Receptor 1 Antibody - Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GALR1 / Galanin Receptor 1 Antibody - Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GALR1 / Galanin Receptor 1 Antibody - Anti-GALR1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GALR1 / Galanin Receptor 1 Antibody - Lung, non small cell carcinoma
GALR1 / Galanin Receptor 1 Antibody - Brain, Parkinson's soft body
GALR1 / Galanin Receptor 1 Antibody - Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GALR1 / Galanin Receptor 1 Antibody - Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GALR1 / Galanin Receptor 1 Antibody - Anti-GALR1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human GALR1 / Galanin Receptor 1 Antibody (N‑Terminus, IHC) LS‑A4105

PathPlus™ Polyclonal Rabbit anti‑Human GALR1 / Galanin Receptor 1 Antibody (N‑Terminus, IHC) LS‑A4105

Antibody:
Rabbit Polyclonal to Human GALR1 / Galanin Receptor 1
Application:
IHC, IHC-P, ICC
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A4105-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human GALR1 / Galanin Receptor 1
Application:
IHC, IHC-P, ICC
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Galanin receptor 1 (GALR1) mediates the effects of the peptide galanin in a wide variety of tissues. Unlike GALR2, the primary signaling mechanism of GALR1 is by inhibiting adenylate cyclase through Gi. GALR1 regulates the GnRH neuroendocrine axis with its expression in POMC neurons. Pathogens like E. coli can cause diarrhea by increasing expression of Galanin Receptor 1 in the epithelial cells lining the colon, resulting in increased secretion of colonocyte chloride and fluid. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GALR1 / Galanin Receptor 1
Synonyms
GALR1 | Galanin receptor type 1 | Galanin receptor 1 | Galanin receptor galr1 | Galanin-1 receptor | GALNR1 | Gal receptor 1 | Gal-r1 | Galn1r | Gal-1 receptor | GAL1-R | Galanin r1 receptor | GALNR | GALR-1 | Hugal 1-r
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (19 µg/ml)
  • ICC
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 18 amino acid peptide from N-Terminus extracellular domain of human GALR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (94%); Dog (89%); Panda, Horse (83%).
Blocking Peptide
LS-E28888 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A4105. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human GALR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SSTR5 (50%).
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GALR1 / Galanin Receptor 1
P47211 NM_001480 NP_001471.2

Validation

GALR1 / Galanin Receptor 1 Antibody - Lung, non small cell carcinoma
Lung, non small cell carcinoma
Lung, non small cell carcinoma

GALR1 / Galanin Receptor 1 Antibody - Brain, Parkinson's soft body
Brain, Parkinson's soft body
Brain, Parkinson's soft body

GALR1 / Galanin Receptor 1 Antibody - Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GALR1 / Galanin Receptor 1 Antibody - Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GALR1 / Galanin Receptor 1 Antibody - Anti-GALR1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ GALR1 / Galanin Receptor 1 Antibody (N-Terminus) for IHC, ICC LS-A4105 has an LSBio Rating of
Laboratory Validation Score (5)

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Requested From: United States
Date Requested: 6/4/2020