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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A5097-50 50 µg (1 mg/ml) $425 
FZD9 / Frizzled 9 Antibody - Breast, carcinoma
FZD9 / Frizzled 9 Antibody - Brain, Glioblastoma
FZD9 / Frizzled 9 Antibody - Skin, Malignant Melanoma
FZD9 / Frizzled 9 Antibody - Ovary, carcinoma
FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human brains, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD9 / Frizzled 9 Antibody - Brain, Glioblastoma
FZD9 / Frizzled 9 Antibody - Breast, carcinoma
FZD9 / Frizzled 9 Antibody - Brain, Glioblastoma
FZD9 / Frizzled 9 Antibody - Skin, Malignant Melanoma
FZD9 / Frizzled 9 Antibody - Ovary, carcinoma
FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human brains, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD9 / Frizzled 9 Antibody - Brain, Glioblastoma
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PathPlus™ Polyclonal FZD9 / Frizzled 9 Antibody (N‑Terminus, IHC) LS‑A5097

PathPlus™ Polyclonal FZD9 / Frizzled 9 Antibody (N‑Terminus, IHC) LS‑A5097

Antibody:
Rabbit Polyclonal to Human FZD9 / Frizzled 9
Application:
IHC, IHC-P
Reactivity:
Human, Dog, Rabbit
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A5097-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human FZD9 / Frizzled 9
Application:
IHC, IHC-P
Reactivity:
Human, Dog, Rabbit
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human FZD9 / Frizzled 9
Synonyms
FZD9 | CD349 | Frizzled homolog 9 | Fz-9 | Frizzled family receptor 9 | Frizzled-9 | Frizzled 9 | Fz9 | HFz9 | CD349 antigen | Frizzled homolog fzd3 | FzE6
Host
Rabbit
Reactivity
Human, Dog, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bovine, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (14 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 14 amino acid peptide from N-Terminus extracellular domain of human FZD9 / Frizzled 9. Percent identity with other species by BLAST analysis: Human, Gibbon, Dog, Rabbit (100%); Mouse, Rat, Hamster, Bovine (93%); Panda (86%).
Blocking Peptide
LS-E29032 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A5097. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human FZD9 / Frizzled 9. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About FZD9 / Frizzled 9
O00144 NM_003508 NP_003499.1

Validation

FZD9 / Frizzled 9 Antibody - Breast, carcinoma
Breast, carcinoma
Breast, carcinoma

FZD9 / Frizzled 9 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

FZD9 / Frizzled 9 Antibody - Skin, Malignant Melanoma
Skin, Malignant Melanoma
Skin, Malignant Melanoma

FZD9 / Frizzled 9 Antibody - Ovary, carcinoma
Ovary, carcinoma
Ovary, carcinoma

FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD9 / Frizzled 9 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD9 / Frizzled 9 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD9 / Frizzled 9 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD9 / Frizzled 9 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human brains, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD9 / Frizzled 9 antibody IHC of human brains, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD9 / Frizzled 9 antibody IHC of human brains, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FZD9 / Frizzled 9 Antibody - Anti-FZD9 / Frizzled 9 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD9 / Frizzled 9 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD9 / Frizzled 9 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FZD9 / Frizzled 9 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

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Requested From: United States
Date Requested: 2/25/2020