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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A3921-50 50 µg (1 mg/ml) $425 
DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
DRD4 / Dopamine Receptor D4 Antibody - Brain, Hippocampus, dentate gyrus
DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
DRD4 / Dopamine Receptor D4 Antibody - Brain, Hippocampus, dentate gyrus
DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human DRD4 / Dopamine Receptor D4 Antibody (C‑Terminus, IHC) LS‑A3921

PathPlus™ Polyclonal Rabbit anti‑Human DRD4 / Dopamine Receptor D4 Antibody (C‑Terminus, IHC) LS‑A3921

Note: This antibody replaces LS-C64988
Antibody:
Rabbit Polyclonal to Human DRD4 / Dopamine Receptor D4
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A3921-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human DRD4 / Dopamine Receptor D4
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Dopamine Receptor D4 (DRD4) has been suggested to affect personality, substance dependence, cognition, and emotion. DRD4 binds the antipsychotic medications clozapine and spiperone. The DRD4 gene contains extensive polymorphisms consisting of variable numbers of tandem repeats (VNTR) in sequences corresponding to the third cytoplasmic loop of the receptor; at least 27 different haplotypes encoding 20 different protein variants have been documented. The frequency of the different variants varies among population groups. Studies have suggested a link between VNTR and human personality traits (such as novelty seeking) and diseases (such as schizophrenia, bipolar affective disorder, and Tourette syndrome); however, considerable debates exist regarding the validity and significance of such associations. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human DRD4 / Dopamine Receptor D4
Synonyms
DRD4 | D(4) dopamine receptor | D4DR
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 - 10 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 17 amino acid peptide from C-Terminus of human DRD4 / Dopamine Receptor D4. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Ferret, Panda (88%); Hamster, Elephant, Horse, Pig (82%).
Blocking Peptide
LS-E28845 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A3921. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human DRD4 / Dopamine Receptor D4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HTR1D (65%).
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About DRD4 / Dopamine Receptor D4
P21917 NM_000797 NP_000788.2

Validation

DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

DRD4 / Dopamine Receptor D4 Antibody - Brain, Hippocampus, dentate gyrus
Brain, Hippocampus, dentate gyrus
Brain, Hippocampus, dentate gyrus

DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ DRD4 / Dopamine Receptor D4 Antibody (C-Terminus) for IHC LS-A3921 has an LSBio Rating of
Laboratory Validation Score (5)

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Requested From: United States
Date Requested: 6/1/2020