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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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Catalog Number Size Price
LS-B8612-250 250 µl (0.2 mg/ml) $425 
Cytokeratin AE1+AE3 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Cytokeratin AE1+AE3 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Cytokeratin AE1+AE3 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Cytokeratin AE1+AE3 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Cytokeratin AE1+AE3 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Cytokeratin AE1+AE3 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PathPlus™ Monoclonal Mouse anti‑Human Cytokeratin AE1+AE3 Antibody (clone AE1/AE3, IHC, IF) LS‑B8612

PathPlus™ Monoclonal Mouse anti‑Human Cytokeratin AE1+AE3 Antibody (clone AE1/AE3, IHC, IF) LS‑B8612

Note: This antibody replaces LS-C88102
Antibody:
Mouse Monoclonal to Human Cytokeratin AE1+AE3
Application:
IHC-P, IF
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Rabbit, Chicken
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425 
LS-B8612-250
250 µl
0.2 mg/ml
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Mouse Monoclonal to Human Cytokeratin AE1+AE3
Application:
IHC-P, IF
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Rabbit, Chicken
Format:
Unconjugated, Unmodified

Specifications

Description
Cytokeratin AE1 / AE3 is a keratin cocktail that detects KRT1-8, 10, 14-16 and 19. It does not detect CK17 or CK18, and for this reason some pan-keratin cocktails also contain CAM5.2 (which detects CK18). AE1 / AE3 is used by pathologists to confirm or rule out the epithelial nature of tissue, tumors or components of tumors. Furthermore, it is used in immunohistochemistry to identify metastatic carcinoma in bone marrow and lymph nodes. References: Diagn Cytopathol 2002;27:261, PMID: 12411988; Gynecol Oncol 2007;105:683, PMID: 17442382; Int J Cancer 2007;120:1603, PMID: 17230512
Target
Human Cytokeratin AE1+AE3
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
AE1/AE3
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC - Paraffin (10 µg/ml)
  • Immunofluorescence
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Human epidermal keratin
Presentation
10 mM PBS, pH 7.4, 0.09% Sodium Azide, 0.2% BSA
Storage
Store at 4°C. Avoid freezing.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

Validation

Cytokeratin AE1+AE3 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)

Cytokeratin AE1+AE3 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Cytokeratin AE1+AE3 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ Cytokeratin AE1+AE3 Antibody (clone AE1/AE3) for IHC, IF/Immunofluorescence LS-B8612 has an LSBio Rating of
Laboratory Validation Score (5)

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Requested From: United States
Date Requested: 6/6/2020