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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-B5562-50 50 µg (0.1 mg/ml) $425 
Mucin 2 / MUC2 Antibody - Anti-MUC2 antibody IHC of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Mucin 2 / MUC2 Antibody - Anti-MUC2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Mucin 2 / MUC2 Antibody - Anti-MUC2 antibody IHC of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Mucin 2 / MUC2 Antibody - Anti-MUC2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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PathPlus™ Mucin 2 / MUC2 Antibody Monoclonal ELISA,Flo,IHC,WB LS‑B5562

PathPlus™ Mucin 2 / MUC2 Antibody Monoclonal ELISA,Flo,IHC,WB LS‑B5562

Note: This antibody replaces LS-C134846
Antibody:
Mouse Monoclonal to Human Mucin 2 / MUC2
Application:
IHC, IHC-P, IHC-Fr, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425 
LS-B5562-50
50 µg
0.1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human Mucin 2 / MUC2
Application:
IHC, IHC-P, IHC-Fr, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
MUC2 is a member of the mucin family of secreted glycoproteins that produces an insoluble mucous barrier in the gastrointestinal tract. MUC2 is implicated in the progression of ulcerative colitis, where it is downregulated. It has also been implicated in the formation or colorectal cancers. A MUC2 knockout model in mice demonstrated a propensity for colorectal cancer in its absence, as these mice frequently developed invasive colorectal adenocarcinomas. Staining is expected to be cytoplasmic within intestinal goblet cells and airway epithelium, and potentially in secretions, as well as within mucinous carcinomas of the colon, breast, pancreas, ovary, and stomach. Allen, 1998; Moehle, 2006; Betge, 2016; Velcich, 2002; Oncotarget 2017 8(42):71456; Am J Surg Path 2005 29(3):359
Target
Human Mucin 2 / MUC2
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
Ccp58
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • IHC - Frozen
  • Western blot
  • Flow Cytometry
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic human MUC2 (MI-29) peptide (VNTR region).
Specificity
Reacts with colon gastric cancer cells, normal intestine, colon and salivary gland (immunoperoxidase staining); human colon cancer cell line LS174T by flow cytometry & Western blotting. Epitope defined as -GTQTP- (GlyThrGlnThrPro).
Usage
Identification of MUC2 in Immunohistochemistry, Flow cytometry, Immunoprecipitation, ELISA and Western blotting.
Presentation
PBS, 0.05% Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About Mucin 2 / MUC2
Q02817 NM_002457 NP_002448.3

Validation

Mucin 2 / MUC2 Antibody - Anti-MUC2 antibody IHC of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-MUC2 antibody IHC of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-MUC2 antibody IHC of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

Mucin 2 / MUC2 Antibody - Anti-MUC2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-MUC2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-MUC2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

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Requested From: United States
Date Requested: 12/10/2019