Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
All LSBio Custom kits have been predesigned and all necessary components, including antibodies and standards have been identified. Upon receiving a custom kit order, the kit will be assembled and quality control tested before being shipped out. Kit assembly and testing typically takes 4 to 6 weeks. In most cases the final kit is based on the Sandwich assay principle, with a few being Competitive EIA based. Specifications such as Range, Sensitivity, and Precision are defined upon completion. In the event that the custom kit cannot be successfully developed with 6 weeks of the order date, the customer will be notified and the order canceled at no cost.
LS-F14001 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Rat PKLR. It is based upon a Custom assay principle.
PKLR ElisaKit, PKL ElisaKit, Pyruvate kinase, liver and RBC ElisaKit, Pyruvate kinase type L ElisaKit, Red cell/liver pyruvate kinase ElisaKit, RPK ElisaKit, PK1 ElisaKit, PKR ElisaKit, Pyruvate kinase 1 ElisaKit, Pyruvate kinase isozymes R/L ElisaKit, R-type/L-type pyruvate kinase ElisaKit, PKRL ElisaKit, Pyruvate kinase isozyme R/L ElisaKit
PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.