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Mouse TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F24735

Ordering

Size Price
1 plate $550
Inquire for larger quantities
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Most Popular TNFRSF1B / TNFR2 Elisa Kits

Rat TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F8073
Sandwich ELISA
96-Well Strip Plate
Rat
0.156-10 ng/ml
Colorimetric - 450nm
Cell Lysates, Serum, Tissue Homogenates, Plasma
 Image
Human TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F8503
Sandwich ELISA
96-Well Strip Plate
Human
0.156-10 ng/ml
Colorimetric - 450nm
Serum, Tissue Homogenates, Plasma
 Image
Rat TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) (Custom) - LS-F13829
Sandwich ELISA
96-Well Strip Plate
Rat
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LS-F24735
Sandwich ELISA (enzyme-linked immunosorbent assay) kit
TNFRSF1B / TNFR2
Mouse
For the detection and quantification of endogenous levels of natural and/or recombinant Mouse CD120b proteins.
LS-F24735 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the Quantitative detection of Mouse TNFRSF1B / TNFR2 in samples of Cell Culture Supernatants and Serum. It is based upon a Sandwich assay principle and can be used to detect levels of TNFRSF1B / TNFR2 as low as 1 picograms per milliliter.
All LSBio Custom kits have been predesigned and all necessary components, including antibodies and standards have been identified. Upon receiving a custom kit order, the kit will be assembled and quality control tested before being shipped out. Kit assembly and testing typically takes 4 to 6 weeks. In most cases the final kit is based on the Sandwich assay principle, with a few being Competitive EIA based. Specifications such as Range, Sensitivity, and Precision are defined upon completion. In the event that the custom kit cannot be successfully developed with 6 weeks of the order date, the customer will be notified and the order canceled at no cost.
Cell Culture Supernatants, Serum
96-Well Strip Plate
Colorimetric - 450nm
Quantitative
15.6 - 1000 pg/ml
1 pg/ml
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping. ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
  • Coated 96-well Strip Plate
  • Standard (Lyophilized)
  • Biotinylated Detection Antibody (100x)
  • Avidin-Biotin-HRP Complex (100x)
  • Sample Diluent
  • Biotinylated Detection Antibody Diluent
  • Avidin-Biotin-HRP Complex Diluent
  • Wash Buffer (20x)
  • TMB Substrate
  • Stop Solution
  • Adhesive Plate Sealers
    Tumor necrosis factor receptor 2 (TNFR2) is one of receptors of TNF. TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors (TNFRs), TNFR1 and TNFR2. The genes for TNFR1, a 55-kDa protein, and TNFR2, a 70-kDa protein, have been mapped to human chromosomes 12 (12pter-cen) and 1 (1pter-p32), respectively. TNFR2 was induced on glomerular endothelial cells of nephritic kidneys, and TNFR2 expression on intrinsic cells, but not leukocytes, was essential for glomerulonephritis and glomerular complement deposition. TNFR1 promotes systemic immune responses and renal T cell death, while intrinsic cell TNFR2 plays a critical role in complement-dependent tissue injury. Therefore, therapeutic blockade specifically of TNFR2 may be a promising strategy in the treatment of immune-mediated glomerulonephritis.
Store at 4°C for 6 months or at -20°C for one year. Avoid freeze/thaw cycles.
For research use only.

About TNFRSF1B / TNFR2

P20333 NM_001066 NP_001057.1

TNFRSF1B Elisa Kit, CD120b antigen Elisa Kit, CD120b Elisa Kit, Etanercept Elisa Kit, p75 TNF receptor Elisa Kit, Soluble TNFR1B variant 1 Elisa Kit, TNFBR Elisa Kit, Tumor necrosis factor receptor Elisa Kit, TNF-R-II Elisa Kit, TNF-R75 Elisa Kit, TNFR2 Elisa Kit, p75TNFR Elisa Kit, p80 TNF-alpha receptor Elisa Kit, TBPII Elisa Kit, TNF-R2 Elisa Kit, TNFR80 Elisa Kit, TNF-RII Elisa Kit, TNFR-II Elisa Kit, TNFR1B Elisa Kit

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Requested From: United States
Date Requested: 12/3/2016

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