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Mouse MMP2 ELISA Kit (Sandwich ELISA) - LS-F24871

Ordering

Size Price
1 plate $550
Inquire for larger quantities
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Most Popular MMP2 Elisa Kits

Human MMP2 ELISA Kit (Sandwich ELISA) - LS-F24619
Quantitative Sandwich ELISA
96-Well Strip Plate
Human
312.5-20000 pg/ml
Colorimetric - 450nm
Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
 Image
Pig MMP2 ELISA Kit (Sandwich ELISA) - LS-F7320
Sandwich ELISA
96-Well Strip Plate
Pig
31.2-2000 pg/ml
Colorimetric - 450nm
Cell Lysates, Serum, Tissue Homogenates, Plasma
 Image
Human MMP2 ELISA Kit (Sandwich ELISA) - LS-F2512
Quantitative Sandwich ELISA
96-Well Microplate
Human
156-10000 pg/ml
Colorimetric - 450nm
Cell Culture Supernatants, Serum, Plasma
 Image

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LS-F24871
Sandwich ELISA (enzyme-linked immunosorbent assay) kit
MMP2
Mouse
For the detection and quantification of endogenous levels of natural and/or recombinant Mouse MMP2 proteins.
LS-F24871 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the Quantitative detection of Mouse MMP2 in samples of Cell Culture Supernatants, Plasma and Serum. It is based upon a Sandwich assay principle and can be used to detect levels of MMP2 as low as 10 picograms per milliliter.
All LSBio Custom kits have been predesigned and all necessary components, including antibodies and standards have been identified. Upon receiving a custom kit order, the kit will be assembled and quality control tested before being shipped out. Kit assembly and testing typically takes 4 to 6 weeks. In most cases the final kit is based on the Sandwich assay principle, with a few being Competitive EIA based. Specifications such as Range, Sensitivity, and Precision are defined upon completion. In the event that the custom kit cannot be successfully developed with 6 weeks of the order date, the customer will be notified and the order canceled at no cost.
Cell Culture Supernatants, Plasma, Serum
96-Well Strip Plate
Colorimetric - 450nm
Quantitative
156 - 10000 pg/ml
10 pg/ml
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping. ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
  • Coated 96-well Strip Plate
  • Standard (Lyophilized)
  • Biotinylated Detection Antibody (100x)
  • Avidin-Biotin-HRP Complex (100x)
  • Sample Diluent
  • Biotinylated Detection Antibody Diluent
  • Avidin-Biotin-HRP Complex Diluent
  • Wash Buffer (20x)
  • TMB Substrate
  • Stop Solution
  • Adhesive Plate Sealers
    Type IV collagenase, 72-kD, is officially designated matrix metalloproteinase-2 (MMP2). It is also known as gelatinase, 72-kD. MMP-2 plays an essential role in angiogenesis and arteriogenesis, two processes critical to restoration of tissue perfusion after ischemia. MMP-2 expression is increased in tissue ischemia, but the responsible mechanisms remain unknown. Matrix metalloproteinases (MMPs) catalyze extracellular matrix degradation. Control of their activity is a promising target for therapy of diseases characterized by abnormal connective tissue turnover. MMPs are expressed as latent proenzymes that are activated by proteolytic cleavage that triggers a conformational change in the propeptide (cysteine switch). The structure of proMMP-2 reveals how the propeptide shields the catalytic cleft and that the cysteine switch may operate through cleavage of loops essential for propeptide stability. The gene is localized to 16q21 using somatic cell hybrids and in situ hybridization.
Store at 4°C for 6 months or at -20°C for one year. Avoid freeze/thaw cycles.
For research use only.

About MMP2

P08253 NM_004530 NP_004521.1

MMP2 Elisa Kit, 72 kd type iv collagenase Elisa Kit, 72 kDa gelatinase Elisa Kit, 72 kd gelatinase Elisa Kit, 72 kDa type IV collagenase Elisa Kit, CLG4A Elisa Kit, CLG4 Elisa Kit, GelA Elisa Kit, Gelatinase A Elisa Kit, Matrix metalloproteinase-2 Elisa Kit, MMP-2 Elisa Kit, MONA Elisa Kit, Neutrophil gelatinase Elisa Kit, TBE-1 Elisa Kit, Tbe-1 metalloprotease Elisa Kit, Collagenase type IV-A Elisa Kit, Matrix metalloproteinase-II Elisa Kit, MMP-II Elisa Kit

Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways.

Requested From: United States
Date Requested: 12/4/2016

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