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Mouse MER / MERTK ELISA Kit (Sandwich ELISA) - LS-F24868

Ordering

Size Price
1 plate $550
Inquire for larger quantities
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Most Popular MER / MERTK Elisa Kits

Human MER / MERTK ELISA Kit (Sandwich ELISA) - LS-F8050
Sandwich ELISA
96-Well Strip Plate
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0.313-20 ng/ml
Colorimetric - 450nm
Cell Lysates, Tissue Homogenates
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Mouse MER / MERTK ELISA Kit (Sandwich ELISA) (Custom) - LS-F17192
Sandwich ELISA
96-Well Strip Plate
Mouse
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Rat MER / MERTK ELISA Kit (Sandwich ELISA) (Custom) - LS-F17194
Sandwich ELISA
96-Well Strip Plate
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LS-F24868
Sandwich ELISA (enzyme-linked immunosorbent assay) kit
MER / MERTK
Mouse
For the detection and quantification of endogenous levels of natural and/or recombinant Mouse MERTK proteins.
LS-F24868 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the Quantitative detection of Mouse MER / MERTK in samples of Cell Culture Supernatants, Cell Lysates, Serum and Tissue Homogenates. It is based upon a Sandwich assay principle and can be used to detect levels of MER / MERTK as low as 10 picograms per milliliter.
All LSBio Custom kits have been predesigned and all necessary components, including antibodies and standards have been identified. Upon receiving a custom kit order, the kit will be assembled and quality control tested before being shipped out. Kit assembly and testing typically takes 4 to 6 weeks. In most cases the final kit is based on the Sandwich assay principle, with a few being Competitive EIA based. Specifications such as Range, Sensitivity, and Precision are defined upon completion. In the event that the custom kit cannot be successfully developed with 6 weeks of the order date, the customer will be notified and the order canceled at no cost.
Cell Culture Supernatants, Cell Lysates, Serum, Tissue Homogenates
96-Well Strip Plate
Colorimetric - 450nm
Quantitative
78 - 5000 pg/ml
10 pg/ml
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping. ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
  • Coated 96-well Strip Plate
  • Standard (Lyophilized)
  • Biotinylated Detection Antibody (100x)
  • Avidin-Biotin-HRP Complex (100x)
  • Sample Diluent
  • Biotinylated Detection Antibody Diluent
  • Avidin-Biotin-HRP Complex Diluent
  • Wash Buffer (20x)
  • TMB Substrate
  • Stop Solution
  • Adhesive Plate Sealers
    Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. This gene also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
Store at 4°C for 6 months or at -20°C for one year. Avoid freeze/thaw cycles.
For research use only.

About MER / MERTK

Q12866 NM_006343 NP_006334.2

MERTK Elisa Kit, Eyk Elisa Kit, MER Elisa Kit, MER receptor tyrosine kinase Elisa Kit, Nyk Elisa Kit, Proto-oncogene c-Mer Elisa Kit, RP38 Elisa Kit, STK kinase Elisa Kit, C-mer Elisa Kit, Receptor tyrosine kinase MerTK Elisa Kit, Tyrosine-protein kinase Mer Elisa Kit

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules.

Requested From: United States
Date Requested: 12/5/2016

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