Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
The Smad3 DNA-Binding ELISA detects endogenous levels of total Smad3 protein.
LS-F821 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Human SMAD3 in samples of Cell Lysates and Nuclear Lysates. It is based upon a DNA Binding assay principle.
Cell Lysates, Nuclear Lysates
12 x 8-Well Microstrips
Colorimetric - 450nm (TMB)
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
SMAD3 ElisaKit, HSPC193 ElisaKit, HMAD-3 ElisaKit, HsT17436 ElisaKit, LDS1C ElisaKit, LDS3 ElisaKit, Mad homolog JV15-2 ElisaKit, MAD3 ElisaKit, MADH3 ElisaKit, Mothers against DPP homolog 3 ElisaKit, JV15-2 ElisaKit, SMA- and MAD-related protein 3 ElisaKit, SMAD family member 3 ElisaKit, MAD homolog 3 ElisaKit, HSMAD3 ElisaKit, Mad protein homolog ElisaKit, SMAD 3 ElisaKit
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription.